Virtual Reality in Individuals With Duchenne Muscular Dystrophy

NCT03002298 | Completed

• 1 other identifier: 16796513.1.0000.0065
• Study Type: interventional
• Target: 64
• Locations: 0 countries
• Sites: N/A

Brief Summary

With the growing accessibility of computer-assisted technology, one option for rehabilitation programs for individuals with Duchenne muscular dystrophy (DMD) is the use of virtual reality environments to enhance motor practice. Thus, it is important to examine whether performance improvements in the virtual environment generalize to the natural environment. To examine this issue, we had 64 individuals, 32 of which were individuals with DMD and 32 were typically developing individuals. The groups practiced two coincidence timing tasks. In the more tangible button-press task, the individuals were required to 'intercept' a falling virtual object at the moment it reached the interception point by pressing a key on the computer. In the more abstract task, they were instructed to 'intercept' the virtual object by making a hand movement in a virtual environment using a webcam.

Conditions

Duchenne Muscular Dystrophy

Outcome Measures

Primary Outcomes (1)

• Motor Learning test by using a timing coincident task in virtual reality

  1 day

Study Arms (4)

DMD gesture task

EXPERIMENTAL

Experimental group that made the task using a gesture in front of a webcam

Behavioral: DMD gesture task

DMD button-press task

EXPERIMENTAL

Experimental group that made the task pressing the button

Behavioral: DMD button-press task

Control group gesture task

ACTIVE COMPARATOR

Control group that made the task using a gesture in front of a webcam

Behavioral: Control group gesture task

Control group button-press task

ACTIVE COMPARATOR

Control group that made the task pressing the button

Behavioral: Control group button-press task

Interventions

DMD gesture task BEHAVIORAL

Timing coincident task in a virtual environment, using motor learning protocol in which a gesture in front of a webcam shoub be done to reach the task

DMD gesture task

DMD button-press task BEHAVIORAL

Timing coincident task in a virtual environment, using motor learning protocol in which the task shoub be done by pressing a button on the keyboard

DMD button-press task

Control group gesture task BEHAVIORAL

Timing coincident task in a virtual environment, using motor learning protocol in which a gesture in front of a webcam shoub be done to reach the task

Control group gesture task

Control group button-press task BEHAVIORAL

Timing coincident task in a virtual environment, using motor learning protocol in which the task shoub be done by pressing a button on the keyboard

Control group button-press task

Eligibility Criteria

• Age: 12 Years - 32 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• medical diagnosis of Duchenne Muscular Dystrophy confirmed by molecular method and/or protein expression in skeletal muscle;
• signing of an informed consent form from the individual or person legally responsible.

You may not qualify if:

• presence of associated comorbidities;
• inability in comprehension of the task.

Sponsors & Collaborators

• University of Sao Paulo: lead

MeSH Terms

Conditions

Muscular Dystrophy, Duchenne

Condition Hierarchy (Ancestors)

Muscular Dystrophies; Muscular Disorders, Atrophic; Muscular Diseases; Musculoskeletal Diseases; Neuromuscular Diseases; Nervous System Diseases; Genetic Diseases, X-Linked; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

• Carlos BM Monteiro, Ph.D.

  University of Sao Paulo

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: December 19, 2016
• First Posted: December 23, 2016
• Study Start: January 1, 2016
• Primary Completion: August 1, 2016
• Study Completion: October 1, 2016
• Last Updated: April 11, 2017

Record last verified: 2017-04