CRUSH STUDY: Calculating Readmission Risk by Ultrasound for Heart Failure Failure Study

NCT02996032 | Completed DMC

• 1 other identifier: H-35112
• Study Type: observational
• Target: 187
• Locations: 1 country
• Sites: 1

Brief Summary

This is a study to determine if two ultrasound measures (Corrected Flow Time and B-Lines) can predict patients at higher risk of readmission within 30 days of hospital discharge for decompensated heart failure.

Conditions

Heart Failure

Outcome Measures

Primary Outcomes (1)

• Change in Corrected Flow Time

  Daily corrected flow time measures will be obtained during hospitalization. Mean hospitalization time for the study population is 9 days, but will be measured during the duration of their hospitalization. Changes in corrected flow time values will be assessed for associations with 30 day return visits. 30 Day returns will be determined by medical record review as well as follow up phone calls to patients. Corrected Flow Time is a single measure performed serial with the same units of measure.

  Measured daily during hospitalization and then correlated to 30 day readmissions.Mean hospitalization for the study population is 9 days, but will be measured during the duration of their hospitalization.

Secondary Outcomes (1)

• Change in Pulmonary Ultrasound (B-Lines)

  Measured daily during hospitalization and correlated to 30 day readmissions. Mean hospitalization time for the study population is 9 days, but will be measured during the duration of hospitalization.

Study Arms (1)

Heart Failure

Patients admitted to the hospital with acute decompensated heart failure expected to be hospitalized for at least 72 hours

Other: Vascular and Pulmonary Ultrasound

Interventions

Vascular and Pulmonary Ultrasound OTHER

Heart Failure

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients hospitalized with a diagnosis of acute decompensated heart failure.

You may qualify if:

• English Speaking
• Being admitted for heart failure with expected hospital stay of 72 hours

You may not qualify if:

• Unable to provide consent

Sponsors & Collaborators

• Boston Medical Center: lead
• Heart Failure Society of America: collaborator
• Emergency Medicine Foundation: collaborator

Study Sites (1)

Boston University

Boston, Massachusetts, 02119, United States

Location

MeSH Terms

Conditions

Heart Failure

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases

Study Officials

• Joseph Pare, MD MHS RDMS

  Assistant Professor

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor of Emergency Medicine

Study Record Dates

• First Submitted: November 30, 2016
• First Posted: December 19, 2016
• Study Start: November 1, 2016
• Primary Completion: April 1, 2018
• Study Completion: April 1, 2018
• Last Updated: October 2, 2018

Record last verified: 2018-10

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)