Effect of Vitamin D Status on Clinical Pregnancy Rates Following Intra Cytoplasmic Sperm Injection

NCT02987478 | Unknown

• 1 other identifier: 6789
• Study Type: observational
• Target: 240
• Locations: 1 country
• Sites: 1

Brief Summary

All patients will undergo in vitro fertilization. Serum 25 (OH) D samples will be collected within1 week before oocyte retrieval. Whole blood specimens will be collected in serum separator tubes using acceptable medical techniques to avoid hemolysis. Ultrasound guided fresh embryo transfer will be performed on day 5 after fertilization. clinical pregnancy will be confirmed by observation of intrauterine sac visible on ultrasound performed 4-5 weeks after embryo transfer.

Conditions

Infertility

Keywords

Vitamin D following intra cytoplasmic sperm injection

Outcome Measures

Primary Outcomes (1)

• pregnancy

  4-5 weeks

Eligibility Criteria

• Age: 20 Years - 35 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

* Age between 20 and 35 years old. * Body mass index between 20 - 30. * Unexplained infertility . * Follicle-stimulating hormone level 12 IU/L or lower (baseline level, cycle day 3). * Normal hysteroscopy . * Fresh embryo transfer of 2 or more blastocysts stage. * Embryo transfer on day 5 after fertilization

You may qualify if:

• Age between 20 and 35 years old.
• Body mass index between 20 - 30.
• Unexplained infertility .
• Follicle-stimulating hormone level 12 IU/L or lower (baseline level, cycle day 3).
• Normal hysteroscopy ( healthy uterus with no fibroids or other growths)
• Fresh embryo transfer of 2 or more blastocysts stage.
• Embryo transfer on day 5 after fertilization

You may not qualify if:

• Women younger than 20 years old or older than 35 years old.
• Previous one or more failed IVF.
• Uncorrected congenital or acquired uterine anomalies.
• Other causes of infertility rather than unexplained infertility.
• Less than 2 embryo transfer, cleavage stager frozen embryo transfer.

Sponsors & Collaborators

• Ain Shams Maternity Hospital: lead

Study Sites (1)

Ain Shams University Maternity Hospital

Cairo, Abbassia, 11566, Egypt

RECRUITING

MeSH Terms

Conditions

Infertility

Condition Hierarchy (Ancestors)

Genital Diseases; Urogenital Diseases

Central Study Contacts

Mohammed Samy, MD

CONTACT

+20100 194 7488; dr_hend_kamal@yahoo.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Clinical Professor

Study Record Dates

• First Submitted: November 29, 2016
• First Posted: December 9, 2016
• Study Start: March 1, 2016
• Primary Completion: March 1, 2017
• Study Completion: December 1, 2017
• Last Updated: December 9, 2016

Record last verified: 2016-12

Locations

EG (1)