Dr Solitaire: Assessing Cognitive Performance Through Meaningful Play

NCT02971124 | Active Not Recruiting

• 1 other identifier: S59650
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 2

Brief Summary

To assess cognitive performance by means of the game of Solitaire. In this study, the investigators want to define relevant game metrics, when playing Solitaire, that may be indicative of cognitive performance.

Conditions

eHealth

Keywords

Cognitive Performance; Meaningful Play; Screening test; Dementia

Outcome Measures

Primary Outcomes (1)

• Specification of Cognitive Performance Metrics for the game Solitaire

  From this study, metrics will be defined which can measure cognitive performance in cardgames like Solitaire. Possible candidates are, but are not limited to: situational awareness to measure visual perception and performance on dual tasks to measure divided attention. A more detailed table of possible game metrics of cognitive performance can be found in H. B. Jimison, M. Pavel, P. Bissell, and J. McKanna, "A Framework for Cognitive Monitoring Using Computer Game Interactions," Medinfo 2007 Proc. 12th World Congr. Health Med. Inform. Build. Sustain. Health Syst., p. 1073, 2007.

  1 day

Secondary Outcomes (1)

• Design Guidelines Apps for the Elderly

  1 day

Study Arms (2)

Healthy Elderly

Mild Cognitive Impaired Elderly

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

24-30 participants, both cognitively healthy older persons (n = 12-15) as well as older persons with mild cognitive impairment (MCI) or mild Alzheimer's disease (mAD) (12-15)

You may qualify if:

• For the HEALTHY participants
• The participant has a minimum age of 65 years.
• The participant is living independently or semi-independently at home, service flat or care home.
• The participant has no subjective memory concern as reported by the participant, informant, or clinician.
• The participant has a normal brain function documented by scoring above 27 on the MMSE, above 26 on the MOCA and has a score of 0 for the CDR.
• In the opinion of the investigator, the participant is in stable medical condition and willing and able to perform study procedures in the opinion of the investigator.
• The participant is fluent in written and verbal Dutch.
• For the participants with COGNITIVE IMPAIRMENT:
• The participant has a minimum age of 65 years.
• The participant is living independently or semi-independently at home, service flat or care home.
• In the opinion of the investigator, the participant is in stable medical condition and willing and able to perform study procedures in the opinion of the investigator.
• The participant is fluent in written and verbal Dutch.
• For MCI: MCI patients, at baseline, are diagnosed applying Petersen's diagnostic criteria, i.e., (1) cognitive complaint, preferably corroborated by an informant; (2) objective cognitive impairment, quantified as performance of more than 1.5 SD below the appropriate mean on the neuropsychological subtests (z-score below -1.5); (3) largely normal general cognitive functioning; (4) essentially intact activities of daily living (ADL) (basic and instrumental activities of daily living (iADL) were determined by a clinical interview with the patient and an informant); and (5) not demented.
• For AD:Probable AD according to the National Institute on Aging/Alzheimer's Association Diagnostic Guidelines

Sponsors & Collaborators

• Universitaire Ziekenhuizen KU Leuven: lead
• KU Leuven: collaborator

Study Sites (2)

Jessa Hospital

Hasselt, Limburg, 3500, Belgium

Location

University Hospital Leuven

Leuven, Vlaams-Brabant, 3000, Belgium

Location

Related Publications (1)

• Gielis K, Vanden Abeele ME, De Croon R, Dierick P, Ferreira-Brito F, Van Assche L, Verbert K, Tournoy J, Vanden Abeele V. Dissecting Digital Card Games to Yield Digital Biomarkers for the Assessment of Mild Cognitive Impairment: Methodological Approach and Exploratory Study. JMIR Serious Games. 2021 Nov 4;9(4):e18359. doi: 10.2196/18359.

  PMID: 34734825 DERIVED

MeSH Terms

Conditions

Dementia

Condition Hierarchy (Ancestors)

Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurocognitive Disorders; Mental Disorders

Study Officials

• Vero Vanden Abeele, prof.

  KU Leuven

  STUDY DIRECTOR

• Karsten Gielis, Drs.

  KU Leuven

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 9, 2016
• First Posted: November 22, 2016
• Study Start: December 1, 2017
• Primary Completion: May 1, 2022
• Study Completion: March 1, 2025
• Last Updated: July 3, 2024

Record last verified: 2024-07

Locations

BE (2)