Concurrent Aerobic Exercise and Virtual Reality Cognitive Training

NCT02963415 | Completed

• 1 other identifier: 1610M98324
• Study Type: interventional
• Target: 39
• Locations: 1 country
• Sites: 1

Brief Summary

The study will implement and test a unique Virtual Reality Cognitive Training (VRCT) combined with concurrent cycling on a recumbent stationary cycle, also known as exergame that seamlessly integrates specific cognitive tasks into a virtual environment and is synchronized with cycling to promote cognition.

Conditions

Preclinical Alzheimer's Disease

Keywords

Subjective memory complaint

Outcome Measures

Primary Outcomes (1)

• Feasibility of the exergame development

  development of the exergame prototype by 3 months

  Baseline to 3 months

Secondary Outcomes (3)

• Cycling adherence rate

  3-6 months

• VCRT adherence rate

  3-6 months

• Usability and satisfaction with the exergame

  3-6 months

Study Arms (1)

Virtual Reality Cognitive Training

EXPERIMENTAL

Exergame to stimulate cognition

Behavioral: Exergame

Interventions

Exergame BEHAVIORAL

Participants will take part in the exergame, 3 times a week for a month. The session will start for 30-35 minutes of cycling on recumbent stationary cycles in session 1 and progress to moderate intensity for 50 minutes a session. Participants will do warm-up and cool-down activities before and after cycling. While cycling, participants will be playing virtual reality based games. An exercise interventionist will supervise the sessions and monitor participant's conditions and responses to ensure safety.

Virtual Reality Cognitive Training

Eligibility Criteria

• Age: 65 Years - 99 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)

You may qualify if:

• Cognitive complaint (defined as answering yes to the question "Do you feel that your memory or thinking skills have gotten worse recently?)
• Not engaging in aerobic exercise or cognitive training \>2 days/week, 30 minutes a session in the past 3 months;
• Age 65 years and older

You may not qualify if:

• Resting heart rate \> 100 or \< 50 beats/min;
• Dementia (self-report, diagnosis, or scoring \<18 on the modified Telephone Interview for Cognitive Status;
• Neurological or major psychiatric disorder since memory problem;
• Significant diseases, symptoms, or other factors that make exercise unsafe
• Current enrollment in another intervention study

Sponsors & Collaborators

• University of Minnesota: lead

Study Sites (1)

University of Minnesota

Minneapolis, Minnesota, 55455, United States

Location

MeSH Terms

Interventions

Exergaming

Intervention Hierarchy (Ancestors)

Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Fang Yu, PhD

  University of Minnesota

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 8, 2016
• First Posted: November 15, 2016
• Study Start: March 1, 2019
• Primary Completion: March 31, 2022
• Study Completion: March 31, 2022
• Last Updated: June 8, 2022

Record last verified: 2022-06

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)