NCT02956252

Brief Summary

The aim of this study is to compare early postoperative outcomes of unselected consecutive patients underwent laparoscopic cholecystectomy (LC) under spinal versus general anesthesia.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,500

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jun 2008

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2008

Completed
8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2016

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2016

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

October 30, 2016

Completed
8 days until next milestone

First Posted

Study publicly available on registry

November 7, 2016

Completed
Last Updated

November 7, 2016

Status Verified

November 1, 2016

Enrollment Period

8 years

First QC Date

October 30, 2016

Last Update Submit

November 4, 2016

Conditions

Keywords

cholecystectomy, laparoscopicspinal anesthesiageneral anesthesiacholecystectomy

Outcome Measures

Primary Outcomes (2)

  • Change in pain level for the first day

    Numerical rating scale (NRS) was used

    from baseline to postoperative 1, 2, 4 and 6 hours

  • Change in pain level for the first month

    Numerical rating scale was used

    From postoperative 1 week to 1 month

Secondary Outcomes (4)

  • Complications

    within the postoperative 1 month

  • Mortality

    within the postoperative 1 month

  • Gastrointestinal quality of life index

    change from baseline to postoperative 1 week and 1 month

  • Patient satisfaction

    at postoperative 1 month

Study Arms (2)

Spinal anesthesia group

patients underwent laparoscopic cholecystectomy under spinal anesthesia

Procedure: Spinal anesthesia

General anesthesia

Patients underwent laparoscopic cholecystectomy under general anesthesia

Procedure: General anesthesia

Interventions

Spinal anesthesia was used in patients who underwent LC

Spinal anesthesia group

General anesthesia was used in patients who underwent LC

General anesthesia

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Between June 2008 and June 2016, all consecutive patients who were admitted or referred to the Medical Park Gaziantep Hospital and underwent LC for symptomatic gallbladder disease were included in the study

You may qualify if:

  • All patients who underwent laparoscopic cholecystectomy for symptomatic gallstone disease with no restriction for age, gender, ethnicity, disease severity, and ASA grade.

You may not qualify if:

  • Patients were excluded if they underwent concurrent surgeries, had malignancy suspicion, received or converted to open surgery, and patients who were under spinal anesthesia converted to general anesthesia.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

CholecystitisGallbladder Diseases

Interventions

Anesthesia, SpinalAnesthesia, General

Condition Hierarchy (Ancestors)

Biliary Tract DiseasesDigestive System Diseases

Intervention Hierarchy (Ancestors)

Anesthesia, ConductionAnesthesiaAnesthesia and Analgesia

Study Officials

  • Mehmet Kaplan, M.D.

    Bahcesehir University, BAU

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

October 30, 2016

First Posted

November 7, 2016

Study Start

June 1, 2008

Primary Completion

June 1, 2016

Study Completion

August 1, 2016

Last Updated

November 7, 2016

Record last verified: 2016-11

Data Sharing

IPD Sharing
Will not share