Feasibility of Bright Light Therapy on Fatigue, Sleep and Circadian Activity Rhythms in Lung Cancer Survivors

NCT02954809 | Completed Results FDA Device

• 1 other identifier: 030-702786
• Study Type: interventional
• Target: 14
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to determine the feasibility of a morning bright light therapy intervention for fatigue, sleep disturbances, and circadian activity rhythms in lung cancer survivors.

Conditions

Fatigue; Sleep Disturbance; Circadian Dysregulation

Keywords

fatigue; sleep disturbances; circadian activity rhythms

Outcome Measures

Primary Outcomes (1)

• Study Completion

  The percentage of participants recruited that completed the study

  Baseline

Other Outcomes (9)

• Changes in Quality of Life With theFunctional Assessment of Cancer Therapy - Lung

  5 weeks

• Assessment of Environmental Light With Actigraphy (Actiwatch Spectrum Respironics)

  5 weeks

• Assessement of Chronotype With the Morningness Versus Eveningness Questionnaire

  1 day

Study Arms (2)

Experimental

EXPERIMENTAL

Exposure to morning bright light therapy delivered with Green-Blue Re-Timer glasses for 30 minutes in the morning during one week.

Device: Morning bright light therapy

Attention Control

ACTIVE COMPARATOR

Exposure to dim light delivered with Red-Yellow Re-Timer glasses for 30 minutes in the morning during one week.

Device: Dim light

Interventions

Morning bright light therapy DEVICE

Exposure to morning bright light therapy delivered with Green-Blue Re-Timer glasses for 30 minutes in the morning during one week.

Experimental

Dim light DEVICE

Exposure to dim light with Red-Yellow Re-Timer glasses for 30 minutes in the morning during one week.

Attention Control

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Stage I-III Non-small cell lung cancer survivors
• Must be at \>6-weeks and \< 3 years post-surgical resection
• Must have diagnosis fatigue and/or sleep disturbances

You may not qualify if:

• Individuals clinically unstable.
• Mania, Bipolar disease or seizure disorder
• Macular degeneration or glaucoma.
• Currently receiving chemotherapy or radiation.

Sponsors & Collaborators

• State University of New York at Buffalo: lead
• Oncology Nursing Society: collaborator

Study Sites (1)

SUNY University at Buffalo

Buffalo, New York, 14214, United States

Location

Related Publications (5)

• Dean GE, Redeker NS, Wang YJ, Rogers AE, Dickerson SS, Steinbrenner LM, Gooneratne NS. Sleep, mood, and quality of life in patients receiving treatment for lung cancer. Oncol Nurs Forum. 2013 Sep;40(5):441-51. doi: 10.1188/13.ONF.441-451.

  PMID: 23989018 BACKGROUND

• Ancoli-Israel S, Rissling M, Neikrug A, Trofimenko V, Natarajan L, Parker BA, Lawton S, Desan P, Liu L. Light treatment prevents fatigue in women undergoing chemotherapy for breast cancer. Support Care Cancer. 2012 Jun;20(6):1211-9. doi: 10.1007/s00520-011-1203-z. Epub 2011 Jun 11.

  PMID: 21660669 BACKGROUND

• Jeste N, Liu L, Rissling M, Trofimenko V, Natarajan L, Parker BA, Ancoli-Israel S. Prevention of quality-of-life deterioration with light therapy is associated with changes in fatigue in women with breast cancer undergoing chemotherapy. Qual Life Res. 2013 Aug;22(6):1239-44. doi: 10.1007/s11136-012-0243-2. Epub 2012 Aug 3.

  PMID: 22865153 BACKGROUND

• Ancoli-Israel S, Liu L, Rissling M, Natarajan L, Neikrug AB, Palmer BW, Mills PJ, Parker BA, Sadler GR, Maglione J. Sleep, fatigue, depression, and circadian activity rhythms in women with breast cancer before and after treatment: a 1-year longitudinal study. Support Care Cancer. 2014 Sep;22(9):2535-45. doi: 10.1007/s00520-014-2204-5. Epub 2014 Apr 15.

  PMID: 24733634 BACKGROUND

• Redd WH, Valdimarsdottir H, Wu LM, Winkel G, Byrne EE, Beltre MA, Liebman ES, Erazo T, Hayes JA, Isola L, Scigliano E, Meschian Y, Lutgendorf S, Ancoli-Israel S. Systematic light exposure in the treatment of cancer-related fatigue: a preliminary study. Psychooncology. 2014 Dec;23(12):1431-4. doi: 10.1002/pon.3553. Epub 2014 May 2. No abstract available.

  PMID: 24798589 BACKGROUND

MeSH Terms

Conditions

Fatigue; Parasomnias; Chronobiology Disorders

Condition Hierarchy (Ancestors)

Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Sleep Wake Disorders; Nervous System Diseases; Mental Disorders

Results Point of Contact

• Title: Dr. Carleara Weiss
• Organization: University at Buffalo

carleara@buffalo.edu

716-829-2006

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: DEVICE FEASIBILITY
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: October 26, 2016
• First Posted: November 3, 2016
• Study Start: October 1, 2016
• Primary Completion: January 1, 2018
• Study Completion: January 1, 2018
• Last Updated: May 1, 2025
• Results First Posted: May 1, 2025

Record last verified: 2025-04

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)