NCT02944669

Brief Summary

This study seeks to further evaluate the Multi-Tiered Training Program and to further explore the overall safety profile of the ReWalk Personal Device outside of the institutional setting under conditions of routine medical practice.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jun 2016

Typical duration for all trials

Geographic Reach
1 country

3 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2016

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

October 24, 2016

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 26, 2016

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2019

Completed
Last Updated

February 2, 2017

Status Verified

February 1, 2017

Enrollment Period

3.3 years

First QC Date

October 24, 2016

Last Update Submit

February 1, 2017

Conditions

Outcome Measures

Primary Outcomes (7)

  • Long-term safety of the ReWalk Personal Device for Subjects in institutional and non- institutional environments, as measured by 12-month incidence of all Serious Adverse Events in Subjects

    12 Months

  • Long-term safety of the ReWalk Personal Device for Subjects in institutional and non- institutional environments, as measured by 12-month incidence of falls and fall- associated injuries

    12 Months

  • Long-term safety of the ReWalk Personal Device for Companions in institutional and non-institutional environments, as measured by 12-month incidence of all Serious Adverse Events in Companions

    12 Months

  • Adequacy of the Multi-Tiered Training Program of the ReWalk Personal Device for Subjects, as measured by the proportion of Subjects enrolled in training who successfully complete the intended training

    12 Months

  • Adequacy of the ReWalk Training Program for Subjects, measured by the proportion of Subjects who successfully completed the intended training who are able to demonstrate proficiencies at 12 months after completion of the intended training

    12 Months

  • Adequacy of the Multi-Tiered Training Program of the ReWalk Personal Device for Subjects, as measured by the Subjects' abilities to navigate surfaces and environments outside of the institutional environment in accordance with their training

    12 Months

  • Adequacy of the Multi-Tiered Training Program of the ReWalk Personal Device for Companions, as measured by the proportion of Companions enrolled in training who successfully complete the intended training

    12 Months

Secondary Outcomes (4)

  • Reliability of the ReWalk Personal Device, as measured by the rates of all device malfunctions

    12 Months

  • Adequacy of the Multi-Tiered Training Program of the ReWalk Personal Device for Subjects, as measured by the qualitative Prescribing Physician, Clinical Trainer, Companion, and Subject responses to directed and open-ended questioning

    12 Months

  • Adequacy of the Multi-Tiered Training Program of the ReWalk Personal Device for Companions, as measured by the qualitative Prescribing Physician, Clinical Trainer, Companion, and Subject responses to directed and open-ended questioning

    12 Months

  • Adequacy of the Multi-Tiered Training Program of the ReWalk Personal Device for Clinical Trainers, as measured by the qualitative Clinical Trainer responses to directed and open-ended questioning

    12 Months

Interventions

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Individuals with spinal cord injury at levels T7 to L5 and a prescription for the device.

You may qualify if:

  • For use in institutional and non-institutional environments: Subjects with spinal cord injury at levels T7 to L5.
  • Age ≥ 18 years old;
  • Hands and shoulders can support crutches or a walker;
  • Healthy bone density;
  • Skeleton does not suffer from any fractures;
  • Able to stand using a device such as EasyStand;
  • In general good health;
  • Height is between 160 cm and 190 cm (5'3" - 6'2");
  • Weight does not exceed 100 kg (220 lbs);
  • Proficiency in spoken and written English language.

You may not qualify if:

  • History of severe neurological injuries or disease other than SCI (MS, CP, ALS, TBI, etc.);
  • Severe concurrent medical disease, including infections, circulatory, heart or lung, pressure sores;
  • Severe spasticity (Ashworth 4)
  • Uncontrolled clonus;
  • Unstable spine or unhealed limbs or pelvic fractures;
  • Heterotopic ossification;
  • Significant contractures;
  • Psychiatric or cognitive situations that may interfere with proper operation of the device or participation in this study;
  • Pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Stanford University

Palo Alto, California, 94304, United States

RECRUITING

Casa Colina Hospital

Pomona, California, 91767, United States

RECRUITING

Rehabilitation Hospital of Indiana

Indianapolis, Indiana, 46254, United States

RECRUITING

MeSH Terms

Conditions

Spinal Cord Injuries

Condition Hierarchy (Ancestors)

Spinal Cord DiseasesCentral Nervous System DiseasesNervous System DiseasesTrauma, Nervous SystemWounds and Injuries

Study Officials

  • Mathew Smuck, MD

    Stanford University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 24, 2016

First Posted

October 26, 2016

Study Start

June 1, 2016

Primary Completion

September 1, 2019

Study Completion

September 1, 2019

Last Updated

February 2, 2017

Record last verified: 2017-02

Data Sharing

IPD Sharing
Will share

De-identified IPD will be made available after the 3-, 6-, and 12-month intervals.

Locations