NRS 2002 as a Predictor of Prognosis in COPD With Respiratory Failure

NCT02942797 | Completed

• 1 other identifier: COPD-002
• Study Type: observational
• Target: 520
• Locations: 1 country
• Sites: 1

Brief Summary

This is a prospective study of patients diagnosed with chronic obstructive pulmonary disease (COPD) with respiratory failure and admitted in West China Hospital during April 2017 to March 2019. The following variables will be prospectively studied: age, sex, height, weight, respiratory function indicators, arterial blood gas analysis results, biochemical data, nutritional risk screening 2002 (NRS 2002) score, short-term and long-term prognostic outcomes. The purpose of this study is to assess whether NRS 2002 is a useful prognosis predictor in COPD patients with respiratory failure.

Conditions

Pulmonary Disease, Chronic Obstructive; Respiratory Insufficiency

Outcome Measures

Primary Outcomes (4)

• Predictive value of NRS 2002 in identifying COPD patients with respiratory failure who will have poor prognostic outcomes, in terms of mortality

  up to 2 years

• Predictive value of NRS 2002 in identifying COPD patients with respiratory failure who will have poor prognostic outcomes, in terms of 30-day readmission after discharge

  up to 2 years

• Predictive value of NRS 2002 in identifying COPD patients with respiratory failure who will have poor prognostic outcomes, in terms of length of stay

  up to 2 years

• Predictive value of NRS 2002 in identifying COPD patients with respiratory failure who will have poor prognostic outcomes, in terms of complications

  up to 2 years

Secondary Outcomes (1)

• Collection of Demographics (age, sex)

  up to 2 years

Study Arms (2)

NRS 2002 score ≥ 3

NRS 2002 score < 3

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients diagnosed with chronic obstructive pulmonary disease with respiratory failure during April 2017 to March 2019 at West China Hospital.

You may qualify if:

• Newly diagnosis of COPD at West China Hospital during April 2017 to March 2019
• Partial pressure of O2 (PaO2) \< 60 mmHg and/or partial pressure of CO2 (PaCO2) \>50 mmHg
• Age ≥ 18 years
• Respiratory rates \> 23 bpm

You may not qualify if:

• Pregnancy or during lactation
• Ventilatory dysfunction due to neuromuscular disorders, acute and chronic thromboembolic disease, severe illness in other systems
• Refused to participate in this study

Sponsors & Collaborators

• West China Hospital: lead

Study Sites (1)

West China Hospital

Chengdu, Sichuan, 610041, China

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive; Respiratory Insufficiency

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Respiration Disorders

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator, Master Degree

Study Record Dates

• First Submitted: October 11, 2016
• First Posted: October 24, 2016
• Study Start: April 1, 2017
• Primary Completion: March 22, 2019
• Study Completion: March 22, 2019
• Last Updated: December 19, 2019

Record last verified: 2019-12

Locations

CN (1)