A Comparison of Three Nutritional Assessment Methods Predicting Prognosis in COPD With Respiratory Failure

NCT02942784 | Completed

• 1 other identifier: COPD-001
• Study Type: observational
• Target: 750
• Locations: 1 country
• Sites: 1

Brief Summary

This is a retrospective study of patients diagnosed with chronic obstructive pulmonary disease (COPD) with respiratory failure and admitted in West China Hospital during January 2014 to March 2016 by review of medical records. The following variables will be retrospectively studied: age, sex, marriage, height, weight, respiratory rate, PaO2, PaCO2, nutritional risk screening 2002 (NRS 2002) score, ALB, short-term and long-term prognostic outcomes, and so on. The purpose of this study is to compare the predictive power of three widely used nutritional assessment methods (BMI, NRS 2002 and ALB) predicting the prognostic outcomes in a cohort of COPD patients with respiratory failure.

Conditions

Pulmonary Disease, Chronic Obstructive; Respiratory Insufficiency

Outcome Measures

Primary Outcomes (3)

• Predictive value of nutritional assessment methods in identifying COPD patients with respiratory failure who will have poor prognosis, in terms of in-hospital death

  up to 27 months

• Predictive value of nutritional assessment methods in identifying COPD patients with respiratory failure who will have poor prognosis, in terms of 1-year death after discharge

  up to 27 months

• Predictive value of nutritional assessment methods in identifying COPD patients with respiratory failure who will have poor prognosis, in terms of 30-day readmission after discharge

  up to 27 months

Secondary Outcomes (4)

• Collection of Demographics (age, sex, marriage)

  up to 27 months

• Number of participants with in-hospital death

  up to 27 months

• Number of participants with 1-year death after discharge

  up to 27 months

• Number of participants with 30-day readmission after discharge

  up to 27 months

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients diagnosed with chronic obstructive pulmonary disease with respiratory failure during January 2014 to March 2016 at West China Hospital by review of medical records.

You may qualify if:

• Newly diagnosis of COPD at West China Hospital during January 2014 to March 2016
• Partial pressure of O2 (PaO2) \< 60 mmHg and/or partial pressure of CO2 (PaCO2) \>50 mmHg
• Age ≥ 18 years
• Respiratory rates \> 23 bpm

You may not qualify if:

• Pregnancy or during lactation
• Ventilatory dysfunction due to neuromuscular disorders, acute and chronic thromboembolic disease, severe illness in other systems
• Incomplete medical profiles

Sponsors & Collaborators

• West China Hospital: lead

Study Sites (1)

West China Hospital

Chengdu, Sichuan, 610041, China

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive; Respiratory Insufficiency

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Respiration Disorders

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator, Master Degree

Study Record Dates

• First Submitted: October 10, 2016
• First Posted: October 24, 2016
• Study Start: April 1, 2017
• Primary Completion: May 12, 2017
• Study Completion: May 12, 2017
• Last Updated: December 19, 2019

Record last verified: 2019-12

Locations

CN (1)