NCT02941406

Brief Summary

The aim of the present study is to investigate the reproducibility of the MP3 and to compare the results with conventional perimetry using the Octopus 101 in healthy subjects and patients with macular disease.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
22

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jul 2015

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2015

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2016

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

October 17, 2016

Completed
4 days until next milestone

First Posted

Study publicly available on registry

October 21, 2016

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2016

Completed
Last Updated

October 21, 2016

Status Verified

October 1, 2016

Enrollment Period

6 months

First QC Date

October 17, 2016

Last Update Submit

October 20, 2016

Conditions

Keywords

RetinaPerimetry

Outcome Measures

Primary Outcomes (1)

  • Reproducibility of retinal sensitivity measurements using microperimetry

    Two study measurements are scheduled within one week. Test-retest reproducibility will be assessed for retinal sensitivity using the coefficient of repeatability and Bland-Altman diagrams.

    Two measurement within one week

Secondary Outcomes (1)

  • Comparison of reproducibility of retinal sensitivity measurements assessed with microperimetry and conventional perimetry

    Two measurement within one week

Study Arms (2)

Healthy subjects

* Men and Women aged 18 and older * Normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant * Normal ophthalmological findings unless the investigator considers an abnormality to be clinically irrelevant

Age-related macular degeneration patients

* Men and Women aged 18 and older * Presence of a macular disease (such as dry or exudative age-related macular degeneration, diabetic maculopathy, epiretinal membrane)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

10 healthy subjects 20 macular patients

You may qualify if:

  • Men and Women aged 18 and older
  • Written informed consent
  • Normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant
  • Normal ophthalmological findings unless the investigator considers an abnormality to be clinically irrelevant
  • Men and Women aged 18 and older
  • Written informed consent
  • Presence of a macular disease (such as dry or exudative age-related macular degeneration, diabetic maculopathy, epiretinal membrane)
  • Any of the following will exclude a subject from the study:
  • Any opacities (corneal scar, dense cataract) which interferes with the study relevant measurements
  • Visual acuity \< 0.1 (Snellen)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hanusch-Krankenhaus

Vienna, Vienna, A-1140, Austria

Location

MeSH Terms

Conditions

Macular Degeneration

Condition Hierarchy (Ancestors)

Retinal DegenerationRetinal DiseasesEye Diseases

Study Officials

  • Oliver Findl, MD, Prof.

    Vienna Institute for Research in Ocular Surgery

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

October 17, 2016

First Posted

October 21, 2016

Study Start

July 1, 2015

Primary Completion

January 1, 2016

Study Completion

December 1, 2016

Last Updated

October 21, 2016

Record last verified: 2016-10

Locations