NCT02938117|Unknown
Impact of a Training Program on the Body Composition of Overweight and Obese Young Adults : Concentric Versus Eccentric Exercise
OPEX
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OPEX
Sponsor study identifier
Secondary identifiers
OTHER · 2016-A01185-46
interventional
30
1 country
1
Study Start
January 2017
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2019
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
January 2020
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Nowadays, eccentric exercise can be realized in a dynamic way with an ergocycle wich permits eccentric (ECC) lower limbs contractions at a defined power output. With this type of ergometer, O2 consumption (VO2) in ECC is three fold lower than in concentric (CON) for the same power output. Consequently, ECC program could be used in chronic disorders with limited capacities, such as obesity. The investigators hypothesis that an eccentric training program, as it will induce higher mechanical constraints, would improve body composition, especially by reducing fat mass. This effect could be explained by an increased rest energy expenditure and a better improvement in biological parameters (particularly lipid profile and insulin-resistance) after ECC training (versus CON training). This study aims to compare the modification of fat mass after an ECC program versus a CON program at the same VO2. The secondary goal is to assess the physiological mechanisms involved in the modification of body composition
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
January 2020
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
October 10, 2016
Actual (reported)October 19, 2016
Actual (reported)January 2017
Date type not reportedThis date has not been verified as actual or estimated.
December 2019
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
January 2020
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
change in total body fat mass (Dual X ray Absorptiometry)
before and after the 12 weeks training program
aerobic capacities (VO2max)
before and after the 12 weeks training program
isometric muscular lower limbs strength
before and after the 12 weeks training program
isokinetic muscular lower limbs strength
before and after the 12 weeks training program
rest energy expenditure (indirect calorimetry)
before and after the 12 weeks training program
biological parameters (plasma lipid profile)
before and after the 12 weeks training program
Thirty adults will be randomized into 2 groups: CON or EXC. The patients of ECC group will follow habituation sessions (2weeks) to avoid the secondary muscular effects of high intensity eccentric exercise
Thirty adults will be randomized into 2 groups: CON or EXC. The patients of ECC group will follow habituation sessions (2weeks) to avoid the secondary muscular effects of high intensity eccentric exercise
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
CHU Clermont-Ferrand
Clermont-Ferrand, 63003, France
Valérie JULIAN
University Hospital, Clermont-Ferrand
First Submitted
October 10, 2016
First Posted
October 19, 2016
Study Start
January 2017
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2019
Estimated (date passed)AVANCE-Houston FRAMEWorks Program Evaluation
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This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
January 2020
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
October 19, 2016
Record last verified: 2016-10
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Source: ClinicalTrials.gov.
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