Assessment of Hydration Status Using Bioelectrical Impedance Vector Analysis

NCT02936440 | Completed

• 1 other identifier: 2009/79
• Study Type: observational
• Target: 224
• Locations: 0 countries
• Sites: N/A

Brief Summary

The state of hyperhydration in critically ill patients with acute kidney injury (AKI) is associated with increased mortality. Bioelectrical impedance vector analysis (BIVA) appears to be a viable method to access the fluid status of critical patients but has never been evaluated in critical patients with AKI. The objective of this study is to evaluate the hydration status using BIVA in critical patients under intensive care at the time of AKI diagnosis and to correlate this measurement with mortality. A sample of 224 patients with AKI will be evaluated by BIVA and followed until they are discharged or death in intensive care unit and the BIVA vectors will be analysed to define differences in hydration characteristics from each group.

Conditions

Acute Kidney Injury; Critical Illness

Keywords

acute kidney injury; intensive care unit; bioelectrical impedance analysis

Outcome Measures

Primary Outcomes (1)

• Proportion of survivors in patients with AKI diagnosis during ICU

  Patients admitted in ICU will be followed up to 2 weeks after AKI diagnosis and survival will be analyzed according to their hydration status assessed by BIVA.

  Up to 12 weeks after AKI diagnosis

Study Arms (1)

critical patients with AKI

Critical patients with AKI will be followed up to 12 weeks after diagnosis

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Intensive care patients who developed acute kidney injury after ICU admission

You may qualify if:

• Patients older than 18 years who developed acute kidney injury after admission in Intensive Care Unit

You may not qualify if:

• Chronic kidney injury, dialysis-dependent chronic kidney injury, acute kidney injury before ICU admission, kidney transplant, morbidity obesity and limb amputation.

Sponsors & Collaborators

• Catholic University of Pelotas: lead

MeSH Terms

Conditions

Acute Kidney Injury; Critical Illness

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Maria Cristina Gonzalez, MD, PhD

  Catholic University of Pelotas

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Full Professor

Study Record Dates

• First Submitted: October 14, 2016
• First Posted: October 18, 2016
• Study Start: May 1, 2011
• Primary Completion: August 1, 2011
• Study Completion: August 1, 2011
• Last Updated: October 18, 2016

Record last verified: 2016-10

Data Sharing

• IPD Sharing: Will not share