Metastatic Spinal Cord Compression (MSCC): Treatment Timing and Survival Rate
1 other identifier
observational
500
0 countries
N/A
Brief Summary
Patients with metastatic spinal cord compression (MSCC) are treated with different options according to the life expectancy. Survival and surgical outcome can be influenced by surgical timing in MSCC patients treated with palliative decompression.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Oct 2016
Longer than P75 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2016
CompletedFirst Submitted
Initial submission to the registry
October 11, 2016
CompletedFirst Posted
Study publicly available on registry
October 17, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2020
CompletedOctober 17, 2016
October 1, 2016
3.8 years
October 11, 2016
October 13, 2016
Conditions
Outcome Measures
Primary Outcomes (1)
survival rate
5 years
Study Arms (3)
Group A
Motor function intact group: received palliative decompression
Group B1
motor deficit group: received palliative decompression within 48 hours after symptoms occured
Group B2
motor deficit group: received palliative decompression 48 hours after symptoms occured
Interventions
palliative decompression to MSCC patients: before motor deficit (Group A), within 48 hours after motor deficit (Group B1), 48 hours after motor deficit (Group B2)
Eligibility Criteria
Patients with metastatic spinal cord compression (MSCC) who underwent palliative decompression.
You may qualify if:
- Patients with metastatic spinal cord compression (MSCC) who underwent palliative decompression in National Taiwan University Hospital after January 1st, 2012.
You may not qualify if:
- Patients with metastatic spinal cord compression (MSCC) who underwent palliative decompression before December 31st, 2011, or those who were not treated in National Taiwan University Hospital.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (2)
Tokuhashi Y, Matsuzaki H, Oda H, Oshima M, Ryu J. A revised scoring system for preoperative evaluation of metastatic spine tumor prognosis. Spine (Phila Pa 1976). 2005 Oct 1;30(19):2186-91. doi: 10.1097/01.brs.0000180401.06919.a5.
PMID: 16205345BACKGROUNDTomita K, Kawahara N, Kobayashi T, Yoshida A, Murakami H, Akamaru T. Surgical strategy for spinal metastases. Spine (Phila Pa 1976). 2001 Feb 1;26(3):298-306. doi: 10.1097/00007632-200102010-00016.
PMID: 11224867BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Shu-Hua Yang, M.D., Ph.D.
National Taiwan University Hospital
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Target Duration
- 2 Years
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 11, 2016
First Posted
October 17, 2016
Study Start
October 1, 2016
Primary Completion
August 1, 2020
Study Completion
August 1, 2020
Last Updated
October 17, 2016
Record last verified: 2016-10
Data Sharing
- IPD Sharing
- Will not share