NCT02932592

Brief Summary

To evaluate the glycemic variations during acute coronary syndrome in non-diabetic patients (euglycemic, or with impaired fasting glucose, or with impaired glucose tolerance)

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
196

participants targeted

Target at P50-P75 for phase_4

Timeline
Completed

Started Mar 2016

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 16, 2016

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

September 30, 2016

Completed
13 days until next milestone

First Posted

Study publicly available on registry

October 13, 2016

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 25, 2017

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2017

Completed
Last Updated

May 26, 2022

Status Verified

May 1, 2022

Enrollment Period

1 year

First QC Date

September 30, 2016

Last Update Submit

May 21, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Glycemic status

    Patients with dysglycemia (not diabetic patients) will be undergone a monitoring of blood glucose with a device till the discharge of the patient. Then, an oral glucose tolerance test (OGTT) will be done to categorize the patient as having impaired fasting glucose (IFG) or impaired glucose tolerance (IGT), or diabetes mellitus.

    15 days

Secondary Outcomes (14)

  • Lipid profile

    15 days

  • Lipid profile

    15 days

  • Lipid profile

    15 days

  • Lipid profile

    15 days

  • Endothelial damage

    15 days

  • +9 more secondary outcomes

Study Arms (1)

Dysglycemic group

EXPERIMENTAL

Patients with dysglycemia (not diabetic patients) will be undergone a monitoring of blood glucose with a device till the discharge of the patient. Then, an oral glucose tolerance test (OGTT) will be done to categorize the patient as having impaired fasting glucose (IFG) or impaired glucose tolerance (IGT), or diabetes mellitus.

Device: Continuous Glucose Monitoring System (i Pro 2 - Medtronic)

Interventions

This device can register blood glucose values and excursions. This device consists of a needle (applied in subcutaneous way) and of a recording device.

Dysglycemic group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • nondiabetic patients
  • acute coronary syndrome

You may not qualify if:

  • diabetic patients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Giuseppe Derosa

Pavia, 27100, Italy

Location

MeSH Terms

Conditions

Acute Coronary Syndrome

Interventions

Continuous Glucose Monitoring

Condition Hierarchy (Ancestors)

Myocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular Diseases

Intervention Hierarchy (Ancestors)

Blood Chemical AnalysisClinical Chemistry TestsClinical Laboratory TechniquesDiagnostic Techniques and ProceduresDiagnosisDiagnostic Techniques, EndocrineMonitoring, PhysiologicInvestigative Techniques

Study Officials

  • Giuseppe Derosa, MD, PhD, FESC

    University of Pavia

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
NA
Masking
NONE
Masking Details
CGMS
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Model Details: CGMS
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, PhD, FESC

Study Record Dates

First Submitted

September 30, 2016

First Posted

October 13, 2016

Study Start

March 16, 2016

Primary Completion

March 25, 2017

Study Completion

October 31, 2017

Last Updated

May 26, 2022

Record last verified: 2022-05

Data Sharing

IPD Sharing
Will not share

Locations