Postprandial Blood Glucose and Insulin Levels Following Consumption of Lentil-containing Food Products
The Love of Lentils (LoL) Study - Phase 2: The Effect of Acute Consumption of Lentil-containing Food Products on Post-prandial Blood Glucose and Insulin in Healthy Adults
1 other identifier
interventional
24
1 country
1
Brief Summary
This study will recruit 20 healthy adults (male and female) to complete 9 study visits where they will consume different food products (chili, soup and muffin) with or without lentils incorporated into the them. Blood samples will be obtained by finger prick before and for 2 hours after the meal and analyzed for glucose and insulin.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Jan 2017
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 25, 2016
CompletedFirst Posted
Study publicly available on registry
October 4, 2016
CompletedStudy Start
First participant enrolled
January 1, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2018
CompletedApril 3, 2018
March 1, 2018
1.2 years
September 25, 2016
March 30, 2018
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Postprandial blood glucose
2 hours postprandial
Postprandial plasma insulin
2 hours postprandial
Study Arms (9)
Small Green Lentil Muffin
EXPERIMENTALMuffin: 25g available carbohydrate from small green lentil
Split Red Lentil Muffin
EXPERIMENTALMuffin: 25g available carbohydrate from split red lentil
Wheat Muffin
PLACEBO COMPARATORMuffin: 25g available carbohydrate from wheat
Small Green Lentil Soup
EXPERIMENTALSoup: 25g available carbohydrate from small green lentil
Split Red Lentil Soup
EXPERIMENTALSoup: 25g available carbohydrate from split red lentil
Potato Soup
PLACEBO COMPARATORSoup: 25g available carbohydrate from potato
Small Green Lentil Chili
EXPERIMENTALChili: 25g available carbohydrate from small green lentil
Split Red Lentil Chili
EXPERIMENTALChili: 25g available carbohydrate from split red lentil
Rice Chili
PLACEBO COMPARATORChili: 25g available carbohydrate from rice
Interventions
Comparison of postprandial blood glucose and insulin following consumption of food products with and without lentils.
Comparison of postprandial blood glucose and insulin following consumption of food products with and without lentils.
Comparison of postprandial blood glucose and insulin following consumption of food products with and without lentils.
Comparison of postprandial blood glucose and insulin following consumption of food products with and without lentils.
Comparison of postprandial blood glucose and insulin following consumption of food products with and without lentils.
Comparison of postprandial blood glucose and insulin following consumption of food products with and without lentils.
Comparison of postprandial blood glucose and insulin following consumption of food products with and without lentils.
Comparison of postprandial blood glucose and insulin following consumption of food products with and without lentils.
Comparison of postprandial blood glucose and insulin following consumption of food products with and without lentils.
Eligibility Criteria
You may qualify if:
- Healthy men and women
- Age 18-40 years (aiming for equal distribution among 18-29, 30-40 years of age)
- BMI 20-30 kg/m2
You may not qualify if:
- Diabetes (fasting blood glucose ≥7.0 mmol/L and/or 2hr blood glucose \>11.1 mmol/L post-75g OGTT) 1
- Impaired Glucose Tolerance (IGT) (Fasting blood glucose 6.1-6.9 mmol/L and/or 2hr blood glucose 7.8-11.0 mmol/L post-75g OGTT) 1
- Blood pressure \>140/90 mm Hg
- Any major medical condition including a history of AIDS or hepatitis
- Medical or surgical event requiring hospitalization within 3 months of randomization
- Any medications except a stable dose (3 months) of oral contraceptives, blood pressure or statin medications
- Natural health products (NHPs) used for glycemic control (all other NHPs okay as long as table for 3 months)
- Tobacco use
- Probiotic supplement use
- Dietary fibre supplement use
- Pulse consumption \>4 servings per week
- Food allergy or non-food life threatening allergy
- Alcohol consumption \>14 drinks/week or \>4 drinks/sitting
- Recent or intended significant weight loss or gain (\>4 kg in previous 3 months)
- Elite athletes
- +1 more criteria
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Guelphlead
- Agriculture and Agri-Food Canadacollaborator
Study Sites (1)
Human Nutraceutical Research Unit
Guelph, Ontario, N1G 2W1, Canada
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Alison M Duncan, PhD, RD
University of Guelph
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- OTHER
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
September 25, 2016
First Posted
October 4, 2016
Study Start
January 1, 2017
Primary Completion
March 1, 2018
Study Completion
March 1, 2018
Last Updated
April 3, 2018
Record last verified: 2018-03
Data Sharing
- IPD Sharing
- Will not share