Multisystemic Therapy-Emerging Adults Trial

NCT02922335 | Completed DMC

• 2 other identifiers: H00090531R01MH108793-01
• Study Type: interventional
• Target: 193
• Locations: 1 country
• Sites: 4

Brief Summary

This study's purpose is to test the effectiveness of a promising intervention for emerging adults (EAs) with mental illness (MI) and serious antisocial behavior in achieving the ultimate outcome of reduced antisocial behavior, and proximal intermediate outcomes. Multisystemic Therapy-Emerging Adults (MST-EA) is an adaptation of MST, a well-established, effective intervention for antisocial behavior in adolescents.

Conditions

Antisocial Behavior

Keywords

Antisocial Behavior; Mental Illness; Emerging Adulthood; Criminal Behavior; Serious Mental Illness

Outcome Measures

Primary Outcomes (1)

• Change in number and severity of criminal charges in official records in the 16 months pre-baseline compared with the 16 months post-baseline.

  Changes from the Baseline in offending, measured in the number of offenses in the Self-Report Offending Scale, during the 16 months post-baseline.

  16 months pre-baseline compared with 16 months post-baseline

Secondary Outcomes (12)

• Changes from Baseline scores compared to 16 months post-Baseline Self-efficacy (measured at 0,2,4,6,8,12 and 16 months).

  Baseline to16 months

• Changes from Baseline scores compared to 16 months post-Baseline Goal directness (measured at 0,2,4,6,8,12 and 16 months).

  Baseline to16 months

• Changes from Baseline scores compared to 16 months post-Baseline Responsibility taking (measured at 0,2,4,6,8,12 and 16 months).

  Baseline to16 months

• Changes from Baseline scores compared to 16 months post-Baseline Symptoms (measured at 0,2,4,6,8,12 and 16 months).

  Baseline to16 months

• Changes from Baseline scores compared to 16 months post-Baseline Treatment Usage (measured at 0,2,4,6,8,12 and 16 months).

  Baseline to16 months

Study Arms (2)

Multisystemic Therapy - Emerging Adults

EXPERIMENTAL

Multisystemic Therapy for Emerging Adults (MST-EA) is designed to help emerging adults (ages 18-21) with mental illness who have been in trouble with the law. MST-EA is a treatment program specifically for emerging adults, to increase skills and capacities that can help them reduce their antisocial behavior and help reduce problems caused by mental health illness, and alcohol or drug use when present.

Behavioral: Multisystemic Therapy for Emerging Adults

Enhanced Treatment as Usual

ACTIVE COMPARATOR

With Enhanced Treatment as Usual (E-TAU) emerging adults will get the treatments that they usually receive when they have a mental illness and have been in trouble with the law. They will receive travel vouchers for attending services, a card with an individualized list of contacts when in crisis, and facilitation with identifying need of services and accessing those services.

Behavioral: Enhanced Treatment as Usual

Interventions

Multisystemic Therapy for Emerging Adults BEHAVIORAL

MST-EA is a home-based therapy in which therapists work closely with each young adult. Therapists often also work with the young person's family, as appropriate. MST-EA is designed to help young people work on their own behavior. This treatment also involves the use of coaches who help young people develop skills for young adulthood.

Also known as: Multisystemic Therapy for Transition-Age Youth (MST-TAY)

Multisystemic Therapy - Emerging Adults

Enhanced Treatment as Usual BEHAVIORAL

Standard services that a young person would receive if they have been in trouble with the law and also have a mental illness.

Also known as: E-TAU

Enhanced Treatment as Usual

Eligibility Criteria

• Age: 16 Years - 26 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• age 16-26
• recent arrest or release from jail/prison/detention (within the past 18 months but excluding arrests for probation/parole violations)
• presence of mood, anxiety, and/or psychotic disorders
• able to reside in a stable community setting (not currently homeless, not currently inpatient; can include individual ready for discharge to the community)
• subject consent

You may not qualify if:

• actively psychotic, suicidal, or homicidal
• Pervasive Developmental Disorders (PDD) or mental retardation
• sex offending as the primary antisocial behavior
• adults unable to consent will also be excluded from this study

Sponsors & Collaborators

• University of Massachusetts, Worcester: lead
• National Institute of Mental Health (NIMH): collaborator
• Oregon Social Learning Center: collaborator
• Connecticut Department of Children and Families: collaborator
• North American Family Institute: collaborator
• Court Support Services Division: collaborator
• Youth Villages: collaborator

Study Sites (4)

North American Family Institute

Hamden, Connecticut, 06518, United States

Location

North American Family Institute

Hartford, Connecticut, 06114, United States

Location

North American Family Institute

New Haven, Connecticut, 06510, United States

Location

Youth Villages

Johnson City, Tennessee, 37601, United States

Location

Related Publications (2)

• Sheidow AJ, McCart MR, Davis M. Multisystemic Therapy for Emerging Adults With Serious Mental Illness and Justice Involvement. Cogn Behav Pract. 2016 Aug;23(3):356-367. doi: 10.1016/j.cbpra.2015.09.003.

  PMID: 28458504 BACKGROUND

• Davis M, Sheidow AJ, McCart MR. Reducing recidivism and symptoms in emerging adults with serious mental health conditions and justice system involvement. J Behav Health Serv Res. 2015 Apr;42(2):172-90. doi: 10.1007/s11414-014-9425-8.

  PMID: 25023764 RESULT

MeSH Terms

Conditions

Antisocial Personality Disorder; Mental Disorders; Criminal Behavior

Condition Hierarchy (Ancestors)

Personality Disorders; Behavior

Study Officials

• Maryann Davis, PhD

  University of Massachusetts, Worcester

  PRINCIPAL INVESTIGATOR

• Ashli Sheidow, PhD

  Oregon Social Learning Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: July 26, 2016
• First Posted: October 4, 2016
• Study Start: September 1, 2016
• Primary Completion: September 1, 2022
• Study Completion: January 31, 2023
• Last Updated: May 22, 2023

Record last verified: 2023-05

Data Sharing

• IPD Sharing: Will share

Locations

US (4)