Etiologies, Investigations and Outcomes of Patients Presenting With Hemoptysis

NCT02913365 | Unknown

• 1 other identifier: 12-099
• Study Type: observational
• Target: 1,000
• Locations: 1 country
• Sites: 1

Brief Summary

The study consist of a retrospective analysis of the etiologies, investigations and outcomes of patients presenting between 2005 to 2010 with hemoptysis in a North-American Tertiary center.

Conditions

Hemoptysis; Haemoptysis; Lung Disease; Pneumonia; Tuberculosis; Bronchiectasis; Respiratory Tract Infections; Respiratory Tract Diseases; Bronchitis; Mycobacterium Infections; Bronchial Disease; Pulmonary Hemorrhage; Signs and Symptoms; Signs and Symptoms, Respiratory; Pathologic Processes; Mycosis; Hemorrhage; Lung Cancer; Pulmonary Embolism; Arteriovenous Fistula

Keywords

Haemoptysis; Hemoptysis; Airway bleeding; Pulmonary hemorrhage

Outcome Measures

Primary Outcomes (1)

• Etiologies of hemoptysis

  Defining the prevalence of pulmonary diseases by measuring the percentage of patients presenting with hemoptysis caused by lung cancer, bronchiectasis, pulmonary embolism, arteriovenous fistula, pneumonia, bronchitis, tuberculosis, mycosis, heart failure, pseudohemoptysis, cryptogenic and other causes.

  5 years

Secondary Outcomes (8)

• Sensitivity of chest X-ray, chest CT-scan and CT-angiography, bronchoscopy, ventilation-perfusion with single-photon emission computed tomography and pulmonary angiography.

  5 years

• All-cause mortality at 2 years

  2 years

• Smoking status

  Day 1

• Age

  Day 1

• Gender

  Day 1

Study Arms (1)

Patients presenting with hemoptysis

Patients over 18 years of age presenting with hemoptysis at the Centre Hospitalier Universitaire de Sherbrooke (CHUS) between the periods of 2005 to 2010.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Any patient presenting with hemoptysis at the Centre Hospitalier Universitaire de Sherbrooke on an outpatient basis, emergency department or hospitalized at hopital Fleurimont or Hotel-Dieu of Sherbrooke.

You may qualify if:

• Any patient over the age of 18 presenting with:
• A diagnosis of hemoptysis on an outpatient basis.
• A diagnosis of hemoptysis during consultation in the emergency department.
• A diagnosis of hemoptysis on the admission sheet.
• A diagnosis of hemoptysis when hospitalized.
• A complication of hemoptysis
• Hemoptysis on the report of the bronchoscopy, chest computed tomography, pulmonary angiography, ventilation-perfusion single-photon emission computed tomography or blood transfusion.

You may not qualify if:

• Patients under 18 years of age.
• Patient who refused investigation for hemoptysis.
• Incomplete medical chart

Sponsors & Collaborators

• Université de Sherbrooke: lead

Study Sites (1)

Centre Hospitalier Universitaire de Sherbrooke

Sherbrooke, Quebec, J1G2E8, Canada

RECRUITING

Related Publications (12)

• Hirshberg B, Biran I, Glazer M, Kramer MR. Hemoptysis: etiology, evaluation, and outcome in a tertiary referral hospital. Chest. 1997 Aug;112(2):440-4. doi: 10.1378/chest.112.2.440.

  PMID: 9266882 BACKGROUND

• Jeudy J, Khan AR, Mohammed TL, Amorosa JK, Brown K, Dyer DS, Gurney JW, MacMahon H, Saleh AG, Vydareny KH; Expert Panel on Thoracic Imaging. ACR Appropriateness Criteria hemoptysis. J Thorac Imaging. 2010 Aug;25(3):W67-9. doi: 10.1097/RTI.0b013e3181e35b0c.

  PMID: 20711032 BACKGROUND

• Alaoui AY, Bartal M, el Boutahiri A, Bouayad Z, Bahlaoui A, el Meziane A, Naciri A. [Clinical characteristics and etiology in hemoptysis in a pneumology service. 291 cases]. Rev Mal Respir. 1992;9(3):295-300. French.

  PMID: 1615202 BACKGROUND

• Reechaipichitkul W, Latong S. Etiology and treatment outcomes of massive hemoptysis. Southeast Asian J Trop Med Public Health. 2005 Mar;36(2):474-80.

  PMID: 15916059 BACKGROUND

• Sanai Raggad S, Abid H, Ghedira H, Tritar F, Hamzaoui A. [Current etiologies of hemoptysis in the elderly: comparative study of 360 cases]. Tunis Med. 2010 Nov;88(11):809-13. French.

  PMID: 21049410 BACKGROUND

• Unsal E, Koksal D, Cimen F, Taci Hoca N, Sipit T. Analysis of patients with hemoptysis in a reference hospital for chest diseases. Tuberk Toraks. 2006;54(1):34-42.

  PMID: 16615016 BACKGROUND

• Prasad R, Garg R, Singhal S, Srivastava P. Lessons from patients with hemoptysis attending a chest clinic in India. Ann Thorac Med. 2009 Jan;4(1):10-2. doi: 10.4103/1817-1737.43062.

  PMID: 19561915 BACKGROUND

• Soares Pires F, Teixeira N, Coelho F, Damas C. Hemoptysis--etiology, evaluation and treatment in a university hospital. Rev Port Pneumol. 2011 Jan-Feb;17(1):7-14. doi: 10.1016/s2173-5115(11)70004-5. English, Portuguese.

  PMID: 21251478 BACKGROUND

• Pedrol E, Fernandez-Sola J, Ferrer M, Barcelo J, Bosch X, Sande L, Camp J, Borras A, Urbano-Marquez A. [Hemoptysis: a prospective study of 108 cases in an emergency service]. Rev Clin Esp. 1991 May;188(9):450-4. Spanish.

  PMID: 1896592 BACKGROUND

• Tsoumakidou M, Chrysofakis G, Tsiligianni I, Maltezakis G, Siafakas NM, Tzanakis N. A prospective analysis of 184 hemoptysis cases: diagnostic impact of chest X-ray, computed tomography, bronchoscopy. Respiration. 2006;73(6):808-14. doi: 10.1159/000091189. Epub 2006 Jan 27.

  PMID: 16446530 BACKGROUND

• Wong CM, Lim KH, Liam CK. The causes of haemoptysis in malaysian patients aged over 60 and the diagnostic yield of different investigations. Respirology. 2003 Mar;8(1):65-8. doi: 10.1046/j.1440-1843.2003.00437.x.

  PMID: 12856744 BACKGROUND

• Haro Estarriol M, Vizcaya Sanchez M, Jimenez Lopez J, Tornero Molina A. [Etiology of hemoptysis: Prospective analysis of 752 cases]. Rev Clin Esp. 2001 Dec;201(12):696-700. doi: 10.1016/s0014-2565(01)70953-8. Spanish.

  PMID: 11835879 BACKGROUND

MeSH Terms

Conditions

Hemoptysis; Lung Diseases; Pneumonia; Tuberculosis; Bronchiectasis; Respiratory Tract Infections; Respiratory Tract Diseases; Bronchitis; Mycobacterium Infections; Bronchial Diseases; Signs and Symptoms; Signs and Symptoms, Respiratory; Pathologic Processes; Mycoses; Hemorrhage; Lung Neoplasms; Pulmonary Embolism; Arteriovenous Fistula

Condition Hierarchy (Ancestors)

Pathological Conditions, Signs and Symptoms; Infections; Actinomycetales Infections; Gram-Positive Bacterial Infections; Bacterial Infections; Bacterial Infections and Mycoses; Lung Diseases, Obstructive; Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Embolism; Embolism and Thrombosis; Vascular Diseases; Cardiovascular Diseases; Arteriovenous Malformations; Vascular Malformations; Cardiovascular Abnormalities; Vascular Fistula; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Fistula; Pathological Conditions, Anatomical

Study Officials

• Brian Grodin-Beaudoin, MD

  Université de Sherbrooke

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Brian Grondin-Beaudoin, MD

CONTACT

18193461110; brian.grondin.beaudoin@usherbrooke.ca

Matthieu Poirier, MD

CONTACT

18193461110; matthieu.benoit.jose.poirier@usherbrooke.ca

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Medical Doctor

Study Record Dates

• First Submitted: September 15, 2016
• First Posted: September 23, 2016
• Study Start: October 1, 2012
• Primary Completion: June 1, 2017
• Study Completion: June 1, 2017
• Last Updated: September 23, 2016

Record last verified: 2016-09

Locations

CA (1)