Osteoarthritis Relationships and Tobacco " Ancillary Study Khoala "

NCT02910830 | Completed

• 1 other identifier: 13-PP-04
• Study Type: observational
• Target: 848
• Locations: 0 countries
• Sites: N/A

Brief Summary

The role of tobacco in osteoarthritis remains controversial. The Khoala cohort is the first multicenter French cohort of subjects with knee and / or hip osteoarthritis prevalent . It guarantees its methodology great representativeness and therefore an interesting material for the study of risk factors in the population. In addition, it should have little here Radiographs of hands for all its patients. It therefore has the opportunity to study a possible relationship between tobacco and hip osteoarthritis , knee and hand but also to study the relationship between tobacco and structural evolution of hip osteoarthritis and / or symptomatic knee.

Conditions

Osteoarthrosis

Outcome Measures

Primary Outcomes (1)

• relationship between smoking and severity of functional impairment in patients with osteoarthritis of hip and knee osteoarthritis using datas from cohort KOHALA

  5 years

Eligibility Criteria

• Age: 40 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients with osteoarthritis of the hip and patients with knee osteoarthritis

You may qualify if:

• Men or women aged between 40 and 75 years
• hip osteoarthritis and / or knee ( stifle ) , unilateral or bilateral , symptomatic with a confirmed diagnosis and meeting the ACR criteria , representative of prevalent cases in France during the constitution of the cohort
• Affiliation to social security

You may not qualify if:

• Presence of a hip or knee prosthesis of the painful joint at baseline ;
• Antecedent osteotomy ;
• severe comorbidity likely to affect significantly the quality of life or induce a major healthcare consumption regardless of osteoarthritis ;
• Knee pain with patellofemoral osteoarthritis isolated , that is to say without tibiofemoral osteoarthritis associated ;
• Other pathologies of these joints
• adults subject to a legal protection measure or unable to express their opposition not to participate in the study

Sponsors & Collaborators

• Centre Hospitalier Universitaire de Nice: lead

MeSH Terms

Conditions

Osteoarthritis

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 5 Years
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 13, 2016
• First Posted: September 22, 2016
• Study Start: September 1, 2014
• Primary Completion: September 1, 2014
• Study Completion: January 1, 2016
• Last Updated: September 22, 2016

Record last verified: 2016-09

Data Sharing

• IPD Sharing: Will not share