Circulating Tumor Material in Colorectal Cancer and Melanoma

NCT02907086 | Completed DMC

• 1 other identifier: UPCC 12916
• Study Type: observational
• Target: 7
• Locations: 1 country
• Sites: 1

Brief Summary

Observational study to allow the collection of blood and medical information to evaluate the role of circulating tumor material in patients with colorectal cancer and melanoma

Conditions

Colorectal Cancer and Melanoma

Outcome Measures

Primary Outcomes (1)

• Number of blood samples collected

  24 months

Study Arms (2)

colorectal cancer

Other: blood collection

melanoma

Other: blood collection

Interventions

blood collection OTHER

Patients will receive a research draw for circulating tumor material analysis with standard clinical labs

colorectal cancer; melanoma

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

colorectal cancer and melanoma patients

You may qualify if:

• The subject must be a patient at the Hospital of the University of Pennsylvania
• Patients with presumed stage II, III, or IV colorectal cancer with planned surgical resection of either the primary tumor or metastatic lesion(s) being evaluated at the Hospital of the University of Pennsylvania
• Patients with histologically confirmed melanoma stage IIb, IIc, IIIa, IIIb, or IIIc/IV scheduled for surgical resection being evaluated at the Hospital of the University of Pennsylvania.
• The subject must be able to provide informed consent or have an acceptable surrogate capable of giving consent on the subject's behalf.
• The subject must be 18 years of age or older.

You may not qualify if:

• The subject is not able to provide informed consent.

Sponsors & Collaborators

• Abramson Cancer Center at Penn Medicine: lead

Study Sites (1)

Abramson Cancer Center of the University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

Location

MeSH Terms

Conditions

Colorectal Neoplasms; Melanoma

Interventions

Blood Specimen Collection

Condition Hierarchy (Ancestors)

Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases; Neuroendocrine Tumors; Neuroectodermal Tumors; Neoplasms, Germ Cell and Embryonal; Neoplasms by Histologic Type; Neoplasms, Nerve Tissue; Nevi and Melanomas; Skin Neoplasms; Skin Diseases; Skin and Connective Tissue Diseases

Intervention Hierarchy (Ancestors)

Specimen Handling; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Punctures; Surgical Procedures, Operative; Investigative Techniques

Study Officials

• Mark O'Hara, MD

  Abramson Cancer Center at Penn Medicine

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 13, 2016
• First Posted: September 20, 2016
• Study Start: July 7, 2017
• Primary Completion: July 1, 2019
• Study Completion: July 1, 2020
• Last Updated: June 6, 2022

Record last verified: 2022-06

Locations

US (1)