Therapeutic Yoga to Improve Function in Parkinson's Disease

NCT02902510 | Completed

• 1 other identifier: Pro00041068
• Study Type: interventional
• Target: 30
• Locations: 0 countries
• Sites: N/A

Brief Summary

This is a single blind, randomized, wait-list controlled, phase II exploratory pilot study.

Conditions

Parkinson's Disease

Keywords

yoga; function; Parkinson's disease; gait; balance

Outcome Measures

Primary Outcomes (3)

• Change in Movement Disorders Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale at 8 weeks

  A performance based assessment of motor function.

  baseline, 8 weeks (post-intervention), and for individuals in the WLC at the end of the 8-week waiting period

• Change in Mini BESTest at 8 weeks

  clinical balance assessment tool that targets 4 balance control systems, including anticipatory postural adjustments, reactive postural control, sensory orientation, and dynamic gait

  baseline, 8 weeks (post-intervention), and for individuals in the WLC at the end of the 8-week waiting period

• Change in Functional Gait Assessment at 8 weeks

  assesses postural stability during 10 walking tasks

  baseline, 8 weeks (post-intervention), and for individuals in the WLC at the end of the 8-week waiting period

Secondary Outcomes (5)

• Change in Freezing of Gait Questionnaire at 8 weeks

  baseline, 8 weeks (post-intervention), and for individuals in the WLC at the end of the 8-week waiting period

• Change in Parkinson's Fatigue Scale at 8 weeks

  baseline, 8 weeks (post-intervention), and for individuals in the WLC at the end of the 8-week waiting period

• Change in Activity Balance Confidence Scale at 8 weeks

  baseline, 8 weeks (post-intervention), and for individuals in the WLC at the end of the 8-week waiting period

• Change in Activity Constraints Scale at 8 weeks

  baseline, 8 weeks (post-intervention), and for individuals in the WLC at the end of the 8-week waiting period

• Change in Parkinson's Disease Questionnaire (PDQ-8) at 8 weeks

  baseline, 8 weeks (post-intervention), and for individuals in the WLC at the end of the 8-week waiting period

Study Arms (2)

Experimental

EXPERIMENTAL

The experimental group is the group that received yoga. The individuals originally assigned to the WLC who completed the yoga intervention AFTER the 8 weeks WLC period also are considered part of the experimental group.

Other: Therapeutic yoga for people with Parkinson's Disease

Wait List Control

NO INTERVENTION

There was no intervention during the WLC.

Interventions

Therapeutic yoga for people with Parkinson's Disease OTHER

Held for 8 weeks, individuals participated in therapeutic yoga 60 minutes 2x/week.

Also known as: Yoga

Experimental

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Diagnosis of Parkinson's Disease with a rating of 1.5-4 on the Modified Hoehn and Yahr Scale of Parkinson's Disease Progression
• Endorsement of FoF,44 able to stand and walk 10 meters with or without an assistive device
• \>18 years old; able to speak English
• Score \>4 out of 6 on the short Mini Mental Status Exam
• Able and willing to attend twice weekly sessions for 8 weeks

You may not qualify if:

• People with self-reported life expectancy \<12 months
• Inability to attend sessions due to transportation issues
• Current involvement with other physical activity (including yoga), rehabilitation, or other intervention studies
• Inability or refusal to provide informed consent

Sponsors & Collaborators

• Clemson University: lead

Related Publications (2)

• Ernst M, Folkerts AK, Gollan R, Lieker E, Caro-Valenzuela J, Adams A, Cryns N, Monsef I, Dresen A, Roheger M, Eggers C, Skoetz N, Kalbe E. Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis. Cochrane Database Syst Rev. 2024 Apr 8;4(4):CD013856. doi: 10.1002/14651858.CD013856.pub3.

  PMID: 38588457 DERIVED

• Ernst M, Folkerts AK, Gollan R, Lieker E, Caro-Valenzuela J, Adams A, Cryns N, Monsef I, Dresen A, Roheger M, Eggers C, Skoetz N, Kalbe E. Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis. Cochrane Database Syst Rev. 2023 Jan 5;1(1):CD013856. doi: 10.1002/14651858.CD013856.pub2.

  PMID: 36602886 DERIVED

MeSH Terms

Conditions

Parkinson Disease

Interventions

Yoga

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases

Intervention Hierarchy (Ancestors)

Mind-Body Therapies; Complementary Therapies; Therapeutics; Spiritual Therapies; Exercise Movement Techniques; Physical Therapy Modalities

Study Officials

• Marieke Van Puymbroeck, PhD

  Clemson University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 5, 2016
• First Posted: September 15, 2016
• Study Start: April 1, 2015
• Primary Completion: December 1, 2015
• Study Completion: April 1, 2016
• Last Updated: September 15, 2016

Record last verified: 2016-09

Data Sharing

• IPD Sharing: Will not share