NCT02891382

Brief Summary

This feasibility study aims to compare the implementation process of three different interventions that use economic incentives to promote lifestyle behavioral changes in patients with type 2 diabetes mellitus, and to identify barriers and facilitators linked to the process of implementing each of the interventions. The interventions are based on economic incentives directed to the patient (individual incentives) or a team comprised by the patient and a partner (mixed incentives). Design: Three-month randomized control feasibility study to test the feasibility of implementing three types of intervention with economic incentives in patients with diabetes mellitus. Setting: Diabetes outpatient clinics from a public hospital in Peru.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
54

participants targeted

Target at P25-P50 for not_applicable diabetes-mellitus-type-2

Timeline
Completed

Started Jul 2016

Shorter than P25 for not_applicable diabetes-mellitus-type-2

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2016

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

August 31, 2016

Completed
7 days until next milestone

First Posted

Study publicly available on registry

September 7, 2016

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2017

Completed
7 years until next milestone

Results Posted

Study results publicly available

February 2, 2024

Completed
Last Updated

February 2, 2024

Status Verified

January 1, 2022

Enrollment Period

7 months

First QC Date

August 31, 2016

Results QC Date

January 4, 2022

Last Update Submit

May 16, 2023

Conditions

Keywords

Diabetes Mellitus, Type 2Weight LossFinancial IncentivesHemoglobin A, Glycosylated

Outcome Measures

Primary Outcomes (1)

  • Change in Glycated Hemoglobin

    HbA1c change at 3 months from baseline

    Baseline and 3 months

Secondary Outcomes (1)

  • Change in Weight

    Baseline and 3 months

Study Arms (3)

Individual incentives - Arm 1

EXPERIMENTAL

This arm receives diabetes education + goal setting + individual rewards

Behavioral: Diabetes educationBehavioral: Goal settingBehavioral: Individual Reward

Mixed incentives (Altruism) - Arm 2

EXPERIMENTAL

This arm receives diabetes education + goal setting + companion support + individual rewards

Behavioral: Diabetes educationBehavioral: Goal settingBehavioral: Companion SupportBehavioral: Individual Reward

Mixed Incentives (Cooperation) - Arm 3

EXPERIMENTAL

This arm receives diabetes education + goal setting + companion support + shared rewards

Behavioral: Diabetes educationBehavioral: Goal settingBehavioral: Companion SupportBehavioral: Shared Reward

Interventions

Participants interact with a diabetes educator (DE), every two weeks.

Individual incentives - Arm 1Mixed Incentives (Cooperation) - Arm 3Mixed incentives (Altruism) - Arm 2
Goal settingBEHAVIORAL

Goals for weight loss and change in levels of HbA1c

Individual incentives - Arm 1Mixed Incentives (Cooperation) - Arm 3Mixed incentives (Altruism) - Arm 2

Patient has a companion/team support partner to support achieving goals.

Mixed Incentives (Cooperation) - Arm 3Mixed incentives (Altruism) - Arm 2

The cash reward is given to the patient with diabetes.

Individual incentives - Arm 1Mixed incentives (Altruism) - Arm 2
Shared RewardBEHAVIORAL

Patients with diabetes and their companion support will each receive 50% of the cash reward.

Mixed Incentives (Cooperation) - Arm 3

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Type 2 diabetes mellitus
  • Body mass index 25-39.9 kg/m2, irrespective of HbA1c status
  • Able to give consent

You may not qualify if:

  • Diagnosis of cancer or another serious comorbidity
  • Pharmacotherapy for weight loss or corticosteroids
  • Pregnant women
  • Blindness, amputation, foot ulcer or being on dialysis
  • Be companion/team support for another participant in the trial
  • Available and committed to supporting the participant in achieving their goals
  • Able to provide consent
  • Physical or mental condition that does not allow him to help the participant to achieve goals

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital Nacional Arzobispo Loayza

Lima, Peru

Location

Related Publications (2)

  • Pesantes MA, Del Valle A, Diez-Canseco F, Bernabe-Ortiz A, Portocarrero J, Trujillo A, Cornejo P, Manrique K, Miranda JJ. Family Support and Diabetes: Patient's Experiences From a Public Hospital in Peru. Qual Health Res. 2018 Oct;28(12):1871-1882. doi: 10.1177/1049732318784906. Epub 2018 Aug 1.

  • Miranda JJ, Lazo-Porras M, Bernabe-Ortiz A, Pesantes MA, Diez-Canseco F, Cornejo SDP, Trujillo AJ. The effect of individual and mixed rewards on diabetes management: A feasibility randomized controlled trial. Wellcome Open Res. 2019 Feb 5;3:139. doi: 10.12688/wellcomeopenres.14824.3. eCollection 2018.

Related Links

MeSH Terms

Conditions

Diabetes Mellitus, Type 2Weight Loss

Interventions

Organizational Objectives

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesBody Weight ChangesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Organization and AdministrationHealth Services Administration

Results Point of Contact

Title
Dr. J Jaime Miranda
Organization
Universidad Peruana Cayetano Heredia

Study Officials

  • Jaime Miranda, MD, PhD

    Universidad Peruana Cayetano Heredia

    PRINCIPAL INVESTIGATOR
  • Antonio Trujillo, PhD

    Johns Hopkins Bloomberg School of Public Health

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 31, 2016

First Posted

September 7, 2016

Study Start

July 1, 2016

Primary Completion

February 1, 2017

Study Completion

February 1, 2017

Last Updated

February 2, 2024

Results First Posted

February 2, 2024

Record last verified: 2022-01

Data Sharing

IPD Sharing
Will share

Following on MRC's data sharing policy, we plan to make our quantitative datasets available in platforms for data sharing (e.g. Figshare, etc.). Qualitative data will be available upon request.

Shared Documents
STUDY PROTOCOL, ICF, ANALYTIC CODE
Time Frame
The dataset with quantitative information will be available within six months from the publication of the main manuscript.
Access Criteria
Contact cronicas@oficinas-upch.pe; maria.pesantes.v@upch.pe; maria.lazo@upch.pe; and/or jaime.miranda@upch.pe
More information

Available IPD Datasets

Individual Participant Data Set Access

Locations