Efficacy of Turmeric in Gingival Massaging and Adjunct to Scaling and Root Planing in Chronic Periodontitis Patient

NCT02890771 | Completed DMC

• 1 other identifier: GDCHIndore
• Study Type: interventional
• Target: 91
• Locations: 0 countries
• Sites: N/A

Brief Summary

Periodontal disease is considered as inflammatory, multifactorial, and threshold disease accompanied by destruction of periodontium and eventually the loss of natural teeth. Periodontal disease is highly prevalent dental disease especially, in developing and underdeveloped countries affecting more or less 80% of the population. For the prevention of this highly prevalent dental affliction, still no effective and practical preventive measures are available which can reduce its high prevalence rate though, lot of research work is going on.

Conditions

Chronic Periodontitis

Keywords

Turmeric; Chronic periodontitis

Outcome Measures

Primary Outcomes (1)

• Plaque Index (Turesky modification of Quigley Hein Index, 1970)

  baseline

Secondary Outcomes (24)

• Plaque Index (Turesky modification of Quigley Hein Index, 1970)

  1 week

• Plaque Index (Turesky modification of Quigley Hein Index, 1970)

  2 week

• Plaque Index (Turesky modification of Quigley Hein Index, 1970)

  4 week

• Plaque Index (Turesky modification of Quigley Hein Index, 1970)

  6 week

• Gingival Index (Loe H and Silness J 1963)

  baseline

Study Arms (3)

Tooth Brushing

ACTIVE COMPARATOR

Tooth brushing with dentifrice

Procedure: Turmeric Massaging; Procedure: SRP with turmeric massaging

Turmeric massaging

EXPERIMENTAL

Tooth Brushing,massaging with whole turmeric powder

Procedure: Tooth Brushing with Dentifrice; Procedure: SRP with turmeric massaging

SRP with turmeric massaging

EXPERIMENTAL

SRP with turmeric massaging on half arch

Procedure: Tooth Brushing with Dentifrice; Procedure: Turmeric Massaging

Interventions

Tooth Brushing with Dentifrice PROCEDURE

Tooth Brushing with Dentifrice (Standard Tooth Brushing technique will be demonstrated by using same type of tooth brush and toothpaste).

SRP with turmeric massaging; Turmeric massaging

Turmeric Massaging PROCEDURE

:-Tooth Brushing with Dentifrice (with same type of tooth brush and toothpaste) and massaging with whole Turmeric Powder.

SRP with turmeric massaging; Tooth Brushing

SRP with turmeric massaging PROCEDURE

on one side of the arch only Scaling and Root Planing(SRP) to be done, while on the other side, after the Scaling and Root Planing massaging with whole Turmeric Powder shall be carried out by the patients/subjects

Tooth Brushing; Turmeric massaging

Eligibility Criteria

• Age: 35 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Cases with moderate to severe form of Generalized Chronic Periodontitis patients of any sex.
• Patients in the age group of 35-65 years, who abide by approved protocol guidelines, and are ready to give written informed consent.

You may not qualify if:

• Any known systemic disease which has effects on periodontium such as diabetes etc.
• Patients on anti-inflammatory, antibiotics and perioceutics, since 3 months.
• Patients who have known allergy to material used for the study.
• Pregnant and lactating mothers.
• Patients had undergone any kind of non-surgical and/or surgical periodontal therapy earlier, in past 6 months.
• Tobacco users.

Sponsors & Collaborators

• Government College of Dentistry, Indore: lead

Related Publications (3)

• Izui S, Sekine S, Maeda K, Kuboniwa M, Takada A, Amano A, Nagata H. Antibacterial Activity of Curcumin Against Periodontopathic Bacteria. J Periodontol. 2016 Jan;87(1):83-90. doi: 10.1902/jop.2015.150260. Epub 2015 Oct 8.

  PMID: 26447754 BACKGROUND

• Farjana HN, Chandrasekaran SC, Gita B. Effect of oral curcuma gel in gingivitis management - a pilot study. J Clin Diagn Res. 2014 Dec;8(12):ZC08-10. doi: 10.7860/JCDR/2014/8784.5235. Epub 2014 Dec 5.

  PMID: 25654020 BACKGROUND

• Zhou T, Chen D, Li Q, Sun X, Song Y, Wang C. Curcumin inhibits inflammatory response and bone loss during experimental periodontitis in rats. Acta Odontol Scand. 2013 Mar;71(2):349-56. doi: 10.3109/00016357.2012.682092. Epub 2012 May 4.

  PMID: 22554269 BACKGROUND

MeSH Terms

Conditions

Chronic Periodontitis

Interventions

Toothbrushing; Dentifrices

Condition Hierarchy (Ancestors)

Periodontitis; Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Oral Hygiene; Preventive Dentistry; Dentistry; Biomedical and Dental Materials; Cosmetics; Specialty Uses of Chemicals; Chemical Actions and Uses; Manufactured Materials; Technology, Industry, and Agriculture

Study Officials

• Dr Subhash Garg, MDS

  Govt. Dental College, Indore

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Post graduate student

Study Record Dates

• First Submitted: September 1, 2016
• First Posted: September 7, 2016
• Study Start: January 1, 2016
• Primary Completion: December 1, 2016
• Study Completion: December 1, 2016
• Last Updated: March 15, 2017

Record last verified: 2017-03