NCT02886949

Brief Summary

This study aims to evaluate the effects of thyroid functions on energy homeostasis and inflammation.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2011

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2011

Completed
3.8 years until next milestone

First Submitted

Initial submission to the registry

September 2, 2015

Completed
1 year until next milestone

First Posted

Study publicly available on registry

September 1, 2016

Completed
4.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2020

Completed
4 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2024

Completed
Last Updated

January 7, 2020

Status Verified

January 1, 2020

Enrollment Period

9.1 years

First QC Date

September 2, 2015

Last Update Submit

January 4, 2020

Conditions

THYROTOXICOSIS

Outcome Measures

Primary Outcomes (1)

  • brain-derived neurotrophic factor

    BDNF

    3 months

Secondary Outcomes (8)

  • vascular cell adhesion molecule 1 (VCAM-1)

    3 months

  • C-reactive protein (CRP)

    3 months

  • Orexin

    3 month

  • Zung Self-Rating Depression Scale (Zung SDS)

    3 month

  • Body composition

    3 month

  • +3 more secondary outcomes

Eligibility Criteria

Age20 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Subjects with a suspicion of thyroid disease.

You may qualify if:

  • Subjects visits outpatient department due to a suspicion of thyroid disease

You may not qualify if:

  • Psychological disorders, severe inflammatory or infection diseases.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital

Taichang, 407, Taiwan

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

Blood samples and urine samples

MeSH Terms

Conditions

Thyrotoxicosis

Condition Hierarchy (Ancestors)

HyperthyroidismThyroid DiseasesEndocrine System Diseases

Study Officials

  • I-Te Lee, MD

    Taichung Veterans General Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

I-Te Lee, MD

CONTACT

itlee@vghtc.gov.tw

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 2, 2015

First Posted

September 1, 2016

Study Start

November 1, 2011

Primary Completion

December 1, 2020

Study Completion

December 1, 2024

Last Updated

January 7, 2020

Record last verified: 2020-01

Data Sharing

IPD Sharing
Will not share

Locations

TW(1)