Value of Radionuclide Cisternography

NCT02876614 | Completed

• 1 other identifier: 69HCL16_0543
• Study Type: observational
• Target: 113
• Locations: 0 countries
• Sites: N/A

Brief Summary

Radionuclide cisternography (RC) is a nuclear medicine examination based on intrathecal injection of \[111In\]diethylenetriaminepentaacetic acid (\[111In\]DTPA). It is prescribed for two recommendations: detection of cerebrospinal fluid (CSF) leak/fistula and diagnosis of normal pressure hydrocephalus. In the search part of CSF leak/fistula, RC offers the benefit of a 24-hour study of CSF unlike other reference tests. In addition to SPECT/CT imaging, the radiopharmacist performs sampling in nasal cavities and throat of the patient to collect a possible flow of CSF. These samples are analysed by radioactivity measurements and bring an added value to the exam. The interest of this examination for management of CSF leak/fistula remains unclear. The aim of this study is to identify and analyse results of all RC examinations performed since 2005 in the Nuclear Medicine department of the Neurological Hospital. The full analysis of patients will allow discussing the role of RC in management of CSF leak/fistulae in clinical practice.

Conditions

CSF Leak; Fistula

Keywords

radionuclide cisternography; CSF leak; imaging

Outcome Measures

Primary Outcomes (1)

• RC /SPECT/CT imaging

  Results of RC including results of SPECT/CT imaging and results of swabs counting (nasal cavities and throat or ear if applicable)

  one week

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

patients who received a convocation for realization of RC

You may qualify if:

• patients who received a convocation for realization of RC (extraction with GERA, software of Nuclear Medicine)

You may not qualify if:

• patients who received a convocation for realization of RC with "valve" protocol

Sponsors & Collaborators

• Hospices Civils de Lyon: lead

MeSH Terms

Conditions

Cerebrospinal Fluid Otorrhea; Fistula

Condition Hierarchy (Ancestors)

Cerebrospinal Fluid Leak; Neurologic Manifestations; Nervous System Diseases; Craniocerebral Trauma; Trauma, Nervous System; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Wounds and Injuries; Pathological Conditions, Anatomical

Study Officials

• Elise LEVIGOUREUX, MD

  Hospices Civils de Lyon

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 9, 2016
• First Posted: August 24, 2016
• Study Start: January 1, 2005
• Primary Completion: December 1, 2005
• Study Completion: December 1, 2005
• Last Updated: August 24, 2016

Record last verified: 2016-08

Data Sharing

• IPD Sharing: Will not share