Familial Hypercholesterolemia Amongst Patients With Acute Coronary Syndrome
Identification of Familial Hypercholesterolemia Amongst Patients With Premature Acute Coronary Syndrome, Follow-up and Treatment
Identification of Familial Hypercholesterolemia Amongst Patients With Premature Acute Coronary Syndrome, Follow-up and Treatment
Sponsor study identifier
observational
500
1 country
1
Study Start
August 2016
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
September 2018
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
September 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Familial hypercholesterolemia (FH) is a most prevalent genetic disorder, defines as high cholesterol level and premature death. The prevalence of FH has been reported in few countries however unknown in Iran. Thus recognize the FH patients, determine the diagnostic strategies and appropriate treatments are important. Also acute coronary syndrome (ACS) is a group of conditions which arises from reduction of blood flow in coronary arteries. Three specific conditions are included: ST elevation myocardial infarction, non ST elevation myocardial infarction and unstable angina. Premature ACS defined by occurrence of ACS\<55 for men and ACS\<60 for women. Studies demonstrated direct connection between familial hypercholesterolemia and occurrence of premature ACS. Investigators intent to detection of FH amongst patients with acute coronary syndrome.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
September 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
August 2016
Date type not reportedThis date has not been verified as actual or estimated.
August 7, 2016
Actual (reported)August 17, 2016
Actual (reported)September 2018
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
September 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Number of Familial hypercholesterolemia amongst patients with premature acute coronary syndrome.
1 year
Survival time after hospitalization.
30 days
Low Density Lipoprotein (LDL-C) at during follow-up.
1 Year
High Density Lipoprotein (HDL) at during follow-up.
1 Year
triglycerides (TG) at during follow-up.
1 Year
LDL-receptor frequency of mutation in Persian Population.
1 Year
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
participating with premature ACS across Isfahan hospitals.
Isfahan cardio vascular research instiute
Isfahan, Iran
Plasma, buffy coat, blood.
First Submitted
August 7, 2016
First Posted
August 17, 2016
Study Start
August 2016
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
September 2018
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This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
September 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
November 30, 2017
Record last verified: 2017-11
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Source: ClinicalTrials.gov.
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