Long Period Observation of Biochemical Survey and Ultrasonography in Thyroid Diseases and Subclinical Thyroid Diseases

NCT02868476 | Unknown

• 1 other identifier: 201606056RINA
• Study Type: observational
• Target: 532
• Locations: 0 countries
• Sites: N/A

Brief Summary

Clinical and subclinical thyroid disease is usually used to describe patients with mild symptoms correlated to hyperthyroid or hypothyroid state. Therapeutic decision for clinical and subclinical thyroid dysfunction should be considered individually. But long term outcome for treatment of such functional and structural thyroid diseases had not been recorded delicately in Taiwan. Further investigations should be observed in the future.The purpose of this study is aiming for early prevention and detection the potential risk factors for thyroid diseases in Taiwan.

Conditions

Thyroid Diseases

Outcome Measures

Primary Outcomes (1)

• Long Period Observation of Biochemical survey and Ultrasonography in Thyroid Diseases and Subclinical Thyroid Diseases

  The study was designed as prospective pattern, and the investigators enrolled new patients with hyperthyroidism/hypothyroidism/nodular goiter/thyroid cancer with long period follow-up, then record thyroid change of thyroid function after treatment of anti-thyroid drugs or thyroid hormone replacement; the clinical outcome of nodular goiter with serial fine needle aspiration cytology and the correlation with thyroid ultrasonography, with the volume/echogenicity/vascularity of nodular goiters. Try to find the correlation of outcome (including how long will the anti-thyroid drugs be stopped without thyroid ablation, the natural course of benign nodular goiters without operation; or thyroid cancer recurrence, thyroid cancer, lymph nodes metastasis or distant metastasis, with surgery/radioactive iodine ablation/target therapy) with regular follow-up in outpatient department via time-dependent manner at least 5 years.

  5 years

Eligibility Criteria

• Age: 20 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Thyroid diseases, age between 20 to 80 years old, consecutive follow-up in outptient department, and we expected to enroll 800 patients in one year, and follow-up with observation for 5 years.

You may qualify if:

• Age 20-80 years old
• Thyroid diseases, including nodular goiter, hyperthyroidism, hypothyroidism and thyroid cancer (before or after operation), consecutive follow-up in outpatient department, and we expected to enroll 800 patients in one year, and follow-up with observation for 5 years.

You may not qualify if:

• N/A

Sponsors & Collaborators

• National Taiwan University Hospital: lead

MeSH Terms

Conditions

Thyroid Diseases

Condition Hierarchy (Ancestors)

Endocrine System Diseases

Study Officials

• CHIH-YUAN WANG, Doctor

  Department of Internal Medicine, National Taiwan University Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 5 Years
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 5, 2016
• First Posted: August 16, 2016
• Study Start: August 19, 2016
• Primary Completion: May 26, 2017
• Study Completion: July 30, 2024
• Last Updated: August 12, 2022

Record last verified: 2022-08