Improving the Diagnosis of Tonsillitis in Emergency Rooms

NCT02858687 | Completed

• 1 other identifier: 2012-46
• Study Type: interventional
• Target: 312
• Locations: 1 country
• Sites: 1

Brief Summary

A point-of-care laboratory (POC) was set at North Hospital, Marseille, France for the diagnosis in less than two hours of tonsillitis caused by known pathogens, close to the reception of Emergency service. In this instance 30% of patients have no etiological diagnosis after the POC tonsillitis tests . This lab has discovered over 200 new species of bacteria in humans, including vector bacteria and opened the field of large Deoxyribonucleic Acid (DNA ) viruses. Also, the laboratory of emerging viruses discovered many Ribonucleic Acid (RNA) viruses transmitted by arthropods. Based on this collection of new pathogens described in POC laboratory, this study proposes to expand the etiological diagnosis strategy of tonsillitis after POC tests. The objective of this study is to implement a new diagnosis strategy relying on the hypothesis that a second pharyngeal swab would improve the etiological diagnosis of tonsillitis of at least 5%.

Conditions

Tonsillitis

Outcome Measures

Primary Outcomes (1)

• Percentage of patients admitted for tonsillitis with a confirmed etiological diagnosis of tonsillitis

  1 day

Study Arms (1)

Patients with clinical diagnosis of tonsillitis

EXPERIMENTAL

Other: Nasopharyngeal swab

Interventions

Nasopharyngeal swab OTHER

Patients with clinical diagnosis of tonsillitis

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Patient admitted at hospital for tonsillitis requiring, for the emergency physician, a microbiological examination with a "POC tonsillitis kit."
• Patient who has freely signed the informed written consent
• Patient affiliated to a social security scheme

You may not qualify if:

• Pregnant woman, parturient or nursing
• Adult patient under guardianship
• Patient deprived of liberty under court order
• Patient refusing or unable to sign the informed consent form.

Sponsors & Collaborators

• Assistance Publique Hopitaux De Marseille: lead

Study Sites (1)

Assistance Publique Hopitaux de Marseille

Marseille, 13354, France

Location

MeSH Terms

Conditions

Tonsillitis

Condition Hierarchy (Ancestors)

Pharyngitis; Respiratory Tract Infections; Infections; Pharyngeal Diseases; Stomatognathic Diseases; Respiratory Tract Diseases; Otorhinolaryngologic Diseases

Study Officials

• Catherine GEINDRE

  Assistance Publique Hôpitaux de Marseille

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 1, 2016
• First Posted: August 8, 2016
• Study Start: February 26, 2013
• Primary Completion: February 8, 2019
• Study Completion: October 27, 2022
• Last Updated: April 21, 2023

Record last verified: 2022-10

Locations

FR (1)