Frailty and Postoperative Outcomes After Emergency General Surgery

NCT02835053 | Completed

• 1 other identifier: DM3
• Study Type: observational
• Target: 150,000
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators will examine the association between preoperative frailty and postoperative outcomes and resource utilization after emergency general surgery.

Conditions

General Surgery; Geriatrics; Outcomes Research

Outcome Measures

Primary Outcomes (1)

• Mortality

  Mortality events will be identified from the registered person's database in Ontario from the date of surgery to 365 days after surgery, at which time participants will be censored

  365 days (from date of surgery)

Secondary Outcomes (4)

• Hospital length of stay

  day of surgery to 365 days after surgery

• Intensive care unit admission

  from date of surgery to 30 days after surgery

• Institutional discharge

  Date of surgery to hospital discharge or 365 days after surgery (at which time participants will be censored)

• Costs

  day of surgery to 365 days after surgery

Study Arms (1)

Emergency General Surgery

All patients having emergency general surgery procedures as defined by Scott et al (JAMA Surgery 2016)

Other: Frailty

Interventions

Frailty OTHER

Participants will be defined as frail based on the Johns Hopkins ACG Frailty Defining Diagnoses Indicator, which will be applied to available health administrative data in the 3 years preceding index hospital admission. If no frailty defining diagnoses are present participants will be defined as not frail

Emergency General Surgery

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All adult residents of Ontario with valid provincial health insurance who have an emergency general surgery procedure (large bowel surgery, small bowel surgery, cholecystectomy, control of hemorrhage from duodenal ulcer, lysis of adhesions, appendectomy, laparotomy)

You may qualify if:

• All residents of Ontario aged more than 65 years on their surgery date with valid provincial health insurance who have an emergency general surgery procedure (large bowel surgery, small bowel surgery, cholecystectomy, control of hemorrhage from duodenal ulcer, lysis of adhesions, appendectomy, laparotomy)

You may not qualify if:

• No valid provincial health insurance

Sponsors & Collaborators

• Ottawa Hospital Research Institute: lead

Study Sites (1)

Ottawa Hospital Research Institute

Ottawa, Ontario, K1Y 4E9, Canada

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 13, 2016
• First Posted: July 15, 2016
• Study Start: April 1, 2002
• Primary Completion: March 1, 2014
• Study Completion: March 1, 2014
• Last Updated: July 15, 2016

Record last verified: 2016-07

Locations

CA (1)