The Effects of Playing High School Football on Later Life Cognitive Functioning and Mental Health

NCT02833129 | Completed

• 1 other identifier: 821703
• Study Type: observational
• Target: 3,904
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purpose of this study is to assess the effect of playing high school football on later in life cognitive functioning and mental health. This is an observational study that will use data from the Wisconsin Longitudinal Study to compare high school football playing graduates in 1957 with comparable non-high school football playing graduates on cognitive functioning and mental health measures when participants are in their 60s.

Conditions

Memory Impairment; Executive Dysfunction; Depression

Outcome Measures

Primary Outcomes (2)

• Summary score of psychological distress/depression at age 65

  Modified CES-D (Center for Epidemiologic Studies Depression Scale) score collected from survey administered when study subjects were approximately 65 years old.

  Collected in 2003-2005 when participants were around 65

• Composite measure of cognition at age 65

  Average of the standardized scores from two cognitive functioning tests. In the first test, Letter Fluency, which measures executive functioning, subjects were asked to name as many words beginning with "L" or "F" as they could in 60 seconds. In the second, Delayed Word Recall, which measures memory and attention, subjects were told a list of 10 words and asked to recall as many as possible 12minutes later.

  Collected in 2003-2005 when participants were around 65

Secondary Outcomes (12)

• Summary score of psychological distress/depression at ages 54 and 72

  Collected in 1992 and 2011 when participants were around 54 and 72 respectively

• Composite measure of cognition at age 72

  Collected in 2011 when participants were around 72

• Score on Letter Fluency test at ages 65 and 72

  Collected in 2003-2005 and 2011 were around 65 and 72 respectively

• Score on Delayed Word Recall test at ages 65 and 72

  Collected in 2003-2005 and 2011 when participants were around 65 and 72 respectively

• Score on Wechsler Adult Intelligence Scale Similarities test at ages 54, 65, and 72

  Collected in 1992, 2003-2005 and 2011 when participants were around 54, 65 and 72 respectively

Other Outcomes (3)

• Occupational Prestige Score

  Measured in 1975 for jobs held between 1964 and 1975

• Total earnings

  1974

• Indicator of regular, vigorous physical activity at age 35

  Measured in 2011

Eligibility Criteria

• Sex: male
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Graduates of Wisconsin high schools in 1957. The data comes from the Wisconsin Longitudinal Study (WLS), a long-term study of a random sample of 10,317 men and women who graduated from Wisconsin high schools in 1957.

You may qualify if:

• \-- Male.

You may not qualify if:

• No yearbook information available to determine football playing status
• Activity participation in yearbook was not recorded under senior photo or in an index.
• Did not played football but played another high contact sport (soccer, hockey, lacrosse or wrestling).

Sponsors & Collaborators

• University of Pennsylvania: lead
• University of Wisconsin, Madison: collaborator
• Moss Rehabilitation Research Institute: collaborator
• Stanford University: collaborator

MeSH Terms

Conditions

Memory Disorders; Depression

Condition Hierarchy (Ancestors)

Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavioral Symptoms; Behavior

Study Officials

• Sameer Deshpande

  University of Pennsylvania

  PRINCIPAL INVESTIGATOR

• Raiden Hasegawaa

  University of Pennsylvania

  PRINCIPAL INVESTIGATOR

• Dylan S Small, PhD

  University of Pennsylvania

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 7, 2016
• First Posted: July 14, 2016
• Study Start: January 1, 1957
• Primary Completion: December 1, 2003
• Study Completion: December 1, 2011
• Last Updated: July 18, 2016

Record last verified: 2016-07