Effect of Thoracic Spine Mobilization on Sympathetic Nervous Systems

NCT02832141 | Completed

• 1 other identifier: Mobilization Thoracic Spine
• Study Type: observational
• Target: 14
• Locations: 1 country
• Sites: 1

Brief Summary

This pilot study aims to i) represents the feasibility of the study design and ii) to point out acute effects of thoracic spine mobilization on skin-blood flow, erythema and the sympathetic nervous system.

Conditions

Erythema

Keywords

Skin blood flow; Skin redness; Sympathetic nervous system; Regional Blood Flow

Outcome Measures

Primary Outcomes (4)

• Feasibility: Adherence of recruited participants

  Defined as the number of drop-outs and presence of participants which invited. Measurement unit: number

  Every 4 weeks up to 2 years

• Feasibility of the investigating procedure

  Measured the burden of testing procedure. Measurement units = number and percentage

  Every 4 weeks up to 2 years

• Feasibility of the mobilization intervention from posterior-to-anterior on thoracic vertebrae

  Measured adverse effects as pain and harm results to participants. Measurement units = number and percentage

  Every 4 weeks up to 2 years

• Feasibility of the mobilization intervention from anterior-to-posterior on thoracic vertebrae

  Measured as adverse effects as pain and harm results to participants. Measurement units = number and percentage.

  Every 4 weeks up to 2 years

Secondary Outcomes (6)

• Rate of heart rate variability (HRV)

  Change from baseline imediately after, 2, 4, 6, 8 and 10 minutes after the intervention

• Rate of systolic blood pressure value (mmHg)

  Change from baseline imediately after, 2, 4, 6, 8 and 10 minutes after the intervention

• Rate of diastolic blood pressure value (mmHg) changes

  Change from baseline imediately after, 2, 4, 6, 8 and 10 minutes after the intervention

• Rate of heartbeat frequency

  Change from baseline imediately after, 2, 4, 6, 8 and 10 minutes after the intervention

• Rate of skin-blood flow variation

  Change from baseline imediately after, 2, 4, 6, 8 and 10 minutes after the intervention

Study Arms (2)

Group A

Group A: immediate effects: T0, Grade 3 central thoracic mobilization from posterior-to-anterior on thoracic vertebrae from T5 to T12, immediate (T1), after 2 (T2), 4 (T3), 6 (T4), 8 (T5) and 10 (T6) minutes, 1 days wash-out period; T7, a grade 3 central thoracic mobilization from anterior-to-posterior on all thoracic vertebrae, immediate T8, after 2 (T9), 4 (T10), 6 (T11), 8 (T12) and 10 (T13) minutes.

Procedure: Mobilization anterior; Procedure: Mobilization posterior

Group B

Group B: immediate effects: T0, 3 central thoracic mobilization from anterior-to-posterior on thoracic vertebrae from T5 to T12, immediate (T1), after 2 (T2), 4 (T3), 6 (T4), 8 (T5) and 10 (T6) minutes, 1 days wash-out period; T7, a grade 3-4 central thoracic mobilization from posterior-to-anterior on all thoracic vertebrae, immediate T8, after 2 (T9), 4 (T10), 6 (T11), 8 (T12) and 10 (T13) minutes.

Procedure: Mobilization anterior; Procedure: Mobilization posterior

Interventions

Mobilization anterior PROCEDURE

Participant in prone position. Central thoracic mobilization from posterior-to-anterior.

Also known as: Thoracic spine mobilization with anterior pressure

Group A; Group B

Mobilization posterior PROCEDURE

Participant in sitting position. Central thoracic mobilization from anteriors-to-posterior.

Also known as: Thoracic spine mobilization with posterior pressure

Group A; Group B

Eligibility Criteria

• Age: 20 Years - 30 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Healthy person between 20 and 30 years.

You may qualify if:

• age 20 - 30 years
• healthy persons

You may not qualify if:

• current pain
• blood pressure medications
• osteoporosis
• cardiac or neurological symptoms
• pregnancy
• thromobosis

Sponsors & Collaborators

• Bern University of Applied Sciences: lead

Study Sites (1)

Bern University of Applied Science, Department Health

Bern, 3008, Switzerland

Location

Related Publications (1)

• Rogan S, Taeymans J, Clarys P, Clijsen R, Tal-Akabi A. Feasibility and effectiveness of thoracic spine mobilization on sympathetic/parasympathetic balance in a healthy population - a randomized controlled double-blinded pilot study. Arch Physiother. 2019 Dec 9;9:15. doi: 10.1186/s40945-019-0067-2. eCollection 2019.

  PMID: 31867125 DERIVED

MeSH Terms

Conditions

Erythema

Condition Hierarchy (Ancestors)

Skin Diseases; Skin and Connective Tissue Diseases; Skin Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Jan Taeymans, PhD

  Bern University of Applied Science, Departement Health

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MSc, MA

Study Record Dates

• First Submitted: July 2, 2016
• First Posted: July 14, 2016
• Study Start: May 1, 2016
• Primary Completion: December 31, 2018
• Study Completion: December 31, 2018
• Last Updated: January 29, 2019

Record last verified: 2019-01

Data Sharing

• IPD Sharing: Will not share

Locations

CH (1)