Electrodermal Patterns of Arousal in Children

NCT02818205 | Completed

• 1 other identifier: Barpak-02-EDA
• Study Type: observational
• Target: 32
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purpose of this study was to explore the feasibility of detecting physiological patterns of arousal to sensory inputs in children with and without Autism Spectrum Disorder (ASD). Accordingly, two questions directed this methodological research investigation: (1) Is there a relationship between rest (tonic) and response (phasic) patterns of arousal among typically developing children and children with ASD?, and (2) Is there a difference in EDA response to sensation between typically developing children and children with ASD?

Conditions

Autism Spectrum Disorder

Outcome Measures

Primary Outcomes (1)

• Electrodermal Activity in response to sensation: tonic and phasic skin conductance in MicroSiemens

  Within six weeks

Study Arms (2)

Children with Autism Spectrum Disorder

Boys between the age of 4 to 11 years old with Autism Spectrum disorder will participate in the Sensory Challenge Protocol which will measure electrodermal activity in response to sensation

Other: Sensory Challenge Protocol

Typically Developing Children

Typically developing boys between the age of 4 to 11 years will participate in the Sensory Challenge Protocol which will measure electrodermal activity in response to sensation.

Other: Sensory Challenge Protocol

Interventions

Sensory Challenge Protocol OTHER

Measurement of electrodermal activity in response to sensation

Children with Autism Spectrum Disorder; Typically Developing Children

Eligibility Criteria

• Age: 4 Years - 11 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

A convenience sample of boys between the ages of 4 - 11 years with and without a diagnosis of Autism Spectrum Disorder were recruited from private and public New Jersey Schools, Barpak Occupational Therapy clinic, Bergenfield, New Jersey and Seton Hall University campus.

You may qualify if:

• Able to sit for 30 minutes and follow simple directions.
• Children with confirmed Autism Spectrum Disorder via School records or parent report.
• Typically developing children free of medical or neurological conditions.

You may not qualify if:

• Medical or neurological conditions other than Autism.
• Hearing loss or visual impairments.
• Children taking medications known to affect arousal.
• Children who are not able to follow simple commands.

Sponsors & Collaborators

• Barpak Geriatric Health Services, Inc. d/b/a Barpak Occupational Therapy: lead

Related Publications (5)

• LACEY JI, LACEY BC. The relationship of resting autonomic activity to motor impulsivity. Res Publ Assoc Res Nerv Ment Dis. 1958;36:144-209. No abstract available.

  PMID: 13527784 BACKGROUND

• MUNDY-CASTLE AC, MCKIEVER BL. The psychophysiological significance of the galvanic skin response. J Exp Psychol. 1953 Jul;46(1):15-24. doi: 10.1037/h0060100. No abstract available.

  PMID: 13069662 BACKGROUND

• Schell AM, Dawson ME, Filion DL. Psychophysiological correlates of electrodermal lability. Psychophysiology. 1988 Nov;25(6):619-32. doi: 10.1111/j.1469-8986.1988.tb01899.x. No abstract available.

  PMID: 3241850 BACKGROUND

• Schoen SA, Miller LJ, Brett-Green BA, Nielsen DM. Physiological and behavioral differences in sensory processing: a comparison of children with autism spectrum disorder and sensory modulation disorder. Front Integr Neurosci. 2009 Nov 3;3:29. doi: 10.3389/neuro.07.029.2009. eCollection 2009.

  PMID: 19915733 BACKGROUND

• Vetrugno R, Liguori R, Cortelli P, Montagna P. Sympathetic skin response: basic mechanisms and clinical applications. Clin Auton Res. 2003 Aug;13(4):256-70. doi: 10.1007/s10286-003-0107-5.

  PMID: 12955550 BACKGROUND

MeSH Terms

Conditions

Autism Spectrum Disorder

Condition Hierarchy (Ancestors)

Child Development Disorders, Pervasive; Neurodevelopmental Disorders; Mental Disorders

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 20, 2016
• First Posted: June 29, 2016
• Study Start: January 1, 2013
• Primary Completion: April 1, 2014
• Study Completion: May 1, 2014
• Last Updated: June 29, 2016

Record last verified: 2016-06

Data Sharing

• IPD Sharing: Will not share