Ambulatory Medication Reconciliation Following Hospital Discharge

NCT00740675 | Unknown

• 1 other identifier: 1U18 HS016790-01
• Study Type: interventional
• Target: 912
• Locations: 1 country
• Sites: 2

Brief Summary

Adverse drug events (ADEs) after hospital discharge are common. The purpose of this research study is see if we can design an electronic tool given to your primary care provider (PCP) that will reduce adverse drug events, hospital readmissions, and emergency department visits after you are discharged from the hospital.

Conditions

Medication Administered in Error; Adverse Drug Events

Keywords

adverse drug events; outpatient

Outcome Measures

Primary Outcomes (1)

• presence of at least one serious medication error per patient

  30 days post-discharge

Secondary Outcomes (2)

• ED visits and non-scheduled hospital readmissions and ED visits

  within 30 days of discharge

• Accuracy of medication list in ambulatory electronic medical record

  30 days post discharge

Study Arms (2)

1

EXPERIMENTAL

At post-discharge follow-up visit with PCP, PCP views: 1. Discharge medication reconciliation screen. 2. Prompts to perform post-discharge reconciliation at the first post-discharge visit.

Other: Outpatient Medication Reconciliation

Uusual care

NO INTERVENTION

PCPs manage the patient's medications after hospital discharge as they normally would.

Interventions

Outpatient Medication Reconciliation OTHER

The post-discharge medication reconciliation module has the following features: 1. Presents the (preadmission) ambulatory medication list and the hospital discharge medication list side-by-side, sorted by class, with all identical medications lined up next to each other and all differences in the two regimens highlighted. 2. Allows users to update the ambulatory medication list with a few keystrokes (i.e., to accept individual changes made during the hospitalization). 3. Allows reconciliation to be performed in full (e.g., for PCPs who are responsible for the entire medication list) or in part (e.g., for specialists).

1

Eligibility Criteria

• Age: 55 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients admitted to BWH or MGH who plan to follow up with a PCP in one of 12 primary care practices affiliated with BWH or MGH.
• Patients will need to meet the following criteria:
• \) be 55 years or older,
• \) be admitted to the participating delivery system's hospital during the study period for a non-psychiatric condition,
• \) have no plans to enter hospice,
• \) be discharged back to the community,
• \) be prescribed 5 or more medications at discharge, including at least one of the following:
• antibiotics,
• insulin,
• antihypertensives,
• anti-rejection,
• antiarrhythmics,
• inhalers,
• antiepileptics,
• antianginals,

You may not qualify if:

• Unable to provide informed consent and has no proxy who administers patient's medications and can provide informed consent

Sponsors & Collaborators

• Brigham and Women's Hospital: lead

Study Sites (2)

Massachusetts General Hospital

Boston, Massachusetts, 02114, United States

Location

Brigham & Women's Hospital

Boston, Massachusetts, 02120, United States

Location

MeSH Terms

Conditions

Drug-Related Side Effects and Adverse Reactions

Condition Hierarchy (Ancestors)

Chemically-Induced Disorders

Study Officials

• David W Bates, MD, MSc

  Brigham and Women's Hospital

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: December 28, 2007
• First Posted: August 25, 2008
• Study Start: April 1, 2008
• Primary Completion: August 1, 2009
• Study Completion: February 1, 2011
• Last Updated: January 6, 2011

Record last verified: 2011-01

Locations

US (2)