Rapid Microbiological Diagnostics for MDRO Quantitative Identification and Resistance Phenotyping to Guide Antibiotic Selection in Wounded Warriors and Veterans - Task 3
Sponsor study identifier
observational
2,102
1 country
1
Study Start
July 2015
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2016
Actual (reported)Study Completion
December 2016
Actual (reported)This research will test a new ultra-rapid technology (called ID/AST Accelerate system) that uses a digital microscope to identify bacteria based on their growth patterns. This method does not have to wait for bacteria to grow in a lab. The new method can identify the type of bacteria within 2 hours of receiving a specimen. The new method also shows the effect of selected antibiotics on the bacteria including multidrug resistant bacteria so that doctors know within 6 hours from specimen collection which antibiotic kills the bacteria. To check the accuracy, speed and impact of the new method on antibiotic prescribing, investigators are proposing a study with two parts; The first part will test the accuracy and speed of the results obtained by the new method. The second part will test if having the results from the new method early would change the antibiotics prescribed to a patient in a simulation experiment. An independent infectious disease physician will be shown the results from the new method and asked if the results were accurate, would it change the antibiotic treatment for the patient.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2016
Actual (reported)Click on a node to explore related trials.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
July 2015
Date type not reportedThis date has not been verified as actual or estimated.
May 11, 2016
Actual (reported)June 13, 2016
Actual (reported)December 2016
Actual (reported)December 2016
Actual (reported)Difference in empiric antimicrobial use
Antibiotic use from the time of specimen collection until antibiotic susceptibility testing results are available to treating clinicians. Antibiotic use will be measured in days of therapy (DOT). DOT in usual care and simulated ID/AST Accelerate system will be compared
1.5 years
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Inpatient or outpatient with a sample being sent for microbiology culture (respiratory, blood or tissue/skin).
Denver Health Medical Center
Denver, Colorado, 80204, United States
Connie S Price, MD
Denver Health
Ivor S Douglas, MD
Denver Health
2,102 participants (actual enrollment reported by the registry).
First Submitted
May 11, 2016
First Posted
June 13, 2016
Study Start
July 2015
Date type not reportedThis date has not been verified as actual or estimated.
Hyperbaric Oxygen, Neutrophil-oxidative Burst, and Cytokines
Contact the study team to confirm eligibility.
Primary Completion
December 2016
Actual (reported)Study Completion
December 2016
Actual (reported)Last Updated
February 2, 2017
Record last verified: 2017-02
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Source: ClinicalTrials.gov.
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