NCT02794311

Brief Summary

The purpose of this study is to specify the psychological, cognitive, neuro-functional and genetic profile associated with binge drinker behaviors among young adults. Results will help identifying more precisely vulnerability factors associated with this pattern of alcohol consumption and guiding prevention efforts.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
125

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2015

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2015

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

May 12, 2016

Completed
28 days until next milestone

First Posted

Study publicly available on registry

June 9, 2016

Completed
3.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 24, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 24, 2019

Completed
Last Updated

January 21, 2026

Status Verified

June 1, 2020

Enrollment Period

4.6 years

First QC Date

May 12, 2016

Last Update Submit

January 19, 2026

Conditions

Outcome Measures

Primary Outcomes (9)

  • Neuropsychological test : Mini International Neuropsychiatric Interview (M.I.N.I)

    day 1

  • Neuropsychological test : Wisconsin Card Sorting Test (WCST)

    V2(3 weeks later)

  • Genetics tests (Single Nucleotide Polymorphism)

    V2(3 weeks later)

  • MRI - signal BOLD (" Blood Oxygen Level Dependant ").

    V3(up to 2 month)

  • Neuropsychological test : Family Informant Schedule and Criteria (FISC)

    day 1

  • Neuropsychological test : Alcohol Use Questionnaire

    day 1

  • Neuropsychological test :Trail Making Test, partie A et B

    V3(up to 2 month)

  • Neuropsychological test : Plus/Minus Test

    V3(up to 2 month)

  • Neuropsychological test :Go/No-Go

    V3(up to 2 month)

Interventions

psychological (personality), neuropsychological (executive functions, memory), genetic (snp polymorphisms) and neuro-anatomical (fMRI)

Eligibility Criteria

Age18 Years - 25 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Males or females
  • Right-handed
  • Aged 18-25 years
  • Native French speaker, able to read French and complete study evaluations
  • Caucasian
  • Able to provide informed written and verbal consent

You may not qualify if:

  • A significant general medical illness, including neurological disorders, mental retardation or head trauma
  • Depression, bipolar disorder, schizophrenia or schizoaffective disorder diagnostic according to DSM-IV
  • Handling of psychotropics substances
  • A sensorial impairment (visual and/or hearing)
  • Women who are pregnant
  • Contraindication to the use of MRI (pacemaker, metal in their body)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Chu Reims

Reims, 51092, France

Location

Related Publications (1)

  • Lannoy S, Dricot L, Benzerouk F, Portefaix C, Barriere S, Quaglino V, Naassila M, Kaladjian A, Gierski F. Neural Responses to the Implicit Processing of Emotional Facial Expressions in Binge Drinking. Alcohol Alcohol. 2021 Feb 24;56(2):166-174. doi: 10.1093/alcalc/agaa093.

MeSH Terms

Conditions

Binge Drinking

Condition Hierarchy (Ancestors)

Alcohol-Related DisordersSubstance-Related DisordersChemically-Induced DisordersAlcohol DrinkingDrinking BehaviorBehaviorMental Disorders

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 12, 2016

First Posted

June 9, 2016

Study Start

February 1, 2015

Primary Completion

September 24, 2019

Study Completion

September 24, 2019

Last Updated

January 21, 2026

Record last verified: 2020-06

Locations