Effect of Maternal Obesity on Labour Induction in Postdate Pregnancy

NCT02788305 | Completed

• 1 other identifier: 9898
• Study Type: observational
• Target: 288
• Locations: 1 country
• Sites: 1

Brief Summary

This study investigate the progression of labour in 144 normal weight pregnant women (BMI \<30) and 144 obese pregnant women (BMI \>30) , not in labor admitted for induction of labor. These women are to be investigated for success of induction of labor.

Conditions

Obesity; Induced; Birth

Outcome Measures

Primary Outcomes (1)

• route of delivery vaginal or caesarean section.

  Partogram is used to access the progress of labour

  48 hours from the start of induction

Secondary Outcomes (1)

• maternal haemorrhage

  48 hours from the start of induction

Study Arms (2)

non obese

BMI\<30. Misoprostol is given for induction of labour according to Bishop score

Drug: Misoprostol

obese

BMI\>30. Misoprostol is given for induction of labour according to Bishop score

Drug: Misoprostol

Interventions

Misoprostol DRUG

Misoprostol 25 micrograms every 6 hours will be given to obese and non obese groups

non obese; obese

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

144 pregnant women with BMI \>= 30 and 144 pregnant women with BMI \<30, post date \>= 41 wks, not in labor admitted in Kaselaini H for induction of labor.

You may qualify if:

• Pregnant woman.
• Post date \>= 41 weeks.
• Absent onset of labor.
• Patient acceptance to join the study after signing an informed consent.

You may not qualify if:

• Placenta previa and or vasa previa.
• Previous caesarean section(CS).
• Multiple gestation
• Any patient who will refuse to be a part of the study.
• Intra- uterine fetal death (IUFD).

Sponsors & Collaborators

• Kasr El Aini Hospital: lead

Study Sites (1)

Kasr wl aini hospitals

Cairo, Greater Cairo, 11956, Egypt

Location

Related Publications (1)

• Maged AM, El-Semary AM, Marie HM, Belal DS, Hany A, Taymour MA, Omran EF, Elbaradie SMY, Mohamed MAK. Effect of maternal obesity on labor induction in postdate pregnancy. Arch Gynecol Obstet. 2018 Jul;298(1):45-50. doi: 10.1007/s00404-018-4767-8. Epub 2018 Apr 2.

  PMID: 29610945 DERIVED

MeSH Terms

Conditions

Obesity

Interventions

Misoprostol

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Prostaglandins E, Synthetic; Prostaglandins, Synthetic; Prostaglandins; Eicosanoids; Fatty Acids, Unsaturated; Fatty Acids; Lipids; Autacoids; Inflammation Mediators; Biological Factors

Study Officials

• Heba M Marie, M.D.

  KasrElaini Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: lecturer at kaselaini hospitals

Study Record Dates

• First Submitted: May 20, 2016
• First Posted: June 2, 2016
• Study Start: May 1, 2016
• Primary Completion: May 30, 2017
• Study Completion: June 30, 2017
• Last Updated: October 16, 2017

Record last verified: 2017-10

Locations

EG (1)