Identifying Barriers and Strategies to Support Self-efficacy for Medication Adherence With Text Messaging

NCT02785848 | Active Not Recruiting

• 1 other identifier: 160750
• Study Type: observational
• Target: 70
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators will explore barriers to improving self-efficacy, or the ability to feel in control of their disease, and medication adherence with text messaging through surveys and interviews with adolescents and adults with SCD cared for at the Vanderbilt Meharry Center of Excellence (VMCE) in Sickle Cell Disease (SCD). The investigators will identify preferences to improve and sustain adherence to daily medication through selection of investigator-proposed or patient-generated text messaging strategies. Finally, the investigators will fill in the literature gaps by describing barriers to self-efficacy and medication adherence among adults with SCD as well as adolescents with SCD who are transitioning to adult care.

Conditions

Sickle Cell Disease

Outcome Measures

Primary Outcomes (1)

• Number of patients with barriers to medication adherence

  High cost, forgetting, side effects, access to medications

  1 year

Secondary Outcomes (1)

• Number of patients that prefer a tailored text messaging technological solution

  1 year

Study Arms (1)

Asthma and/or Sickle Cell Anemia

The investigators will examine patients with sickle cell disease, asthma, or both who are aged 12-70 years who take daily medications.

Other: Interviews and Surveys

Interventions

Interviews and Surveys OTHER

The investigators will perform semi-structured interviews and surveys on this cohort

Asthma and/or Sickle Cell Anemia

Eligibility Criteria

• Age: 12 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The investigators will assess barriers to self-efficacy and medication adherence in the adolescents and adults with sickle cell disease (SCD), asthma, or both, who take daily medications such as hydroxyurea, asthma, or both, have access to mobile phones and/or computers and receive care at the VUMC/Matthew Walker clinic.

You may qualify if:

• Receiving care at the VUMC/Matthew Walker clinic
• Diagnosed with SCD, asthma, or both
• Currently taking daily medications for SCD, such as hydroxyurea, asthma, or both
• Having access to a mobile telephone and/or computer
• Age 12-70 years

You may not qualify if:

• \. Unable to perform interviews or surveys

Sponsors & Collaborators

• Vanderbilt University: lead

Study Sites (1)

Vanderbilt University

Nashville, Tennessee, 37203, United States

Location

MeSH Terms

Conditions

Anemia, Sickle Cell

Interventions

Interviews as Topic; Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Anemia, Hemolytic, Congenital; Anemia, Hemolytic; Anemia; Hematologic Diseases; Hemic and Lymphatic Diseases; Hemoglobinopathies; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Robert Cronin, MD, MS

  Vanderbilt University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: May 25, 2016
• First Posted: May 30, 2016
• Study Start: May 1, 2016
• Primary Completion: May 1, 2022
• Study Completion (Estimated): July 1, 2028
• Last Updated: September 16, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)