Biomechanical Analysis of Dynamic Tasks and Muscular Strength Following Anterior Cruciate Ligament Reconstruction
1 other identifier
observational
1,000
1 country
1
Brief Summary
Background Anterior cruciate ligament (ACL) injuries are one of the most common sporting injuries of the knee. ACL reconstruction (ACLR) has become one of the most common surgical procedures in an attempt to increase joint stability and facilitate athletes to return to sport (RTS). Although ACLR is considered a relatively successful procedure, dynamic control risk factors and strength and power deficits in the involved limb are still present after patients return to sport. Dynamic multi-plane, multi-joint actions such as jumping, landing, change of direction cutting, have been shown to be common mechanisms of injury for the ACL in field sports . Returning to multidirectional sports requires a proficiency and efficiency of movement when carrying out these tasks. There is a lack of standardized, objective criteria to accurately assess an athlete's ability to safely RTS. Therefore, there is a need for research that simultaneously analyses sport specific dynamic tasks (3D motion analysis) and muscular strength/power deficits that may explain poor outcomes following ACLR. This study aims to further investigate movement patterns, limb asymmetry and muscle strength deficit in patients post-surgery to identify risk factors for re-injury and criteria for RTS. The purpose of this study was to:
- 1.Analyse kinematic (movement descriptors) and kinetic (forces that cause movement) during sports specific dynamic tasks at different time-points (6 and 9 months) following ACLR.
- 2.To explore the association of those findings with those who re-injure, those who have persistent knee pain or with those who fail to return to sport.
- 3.To compare the ACLR participants with age and gender matched healthy multidirectional athletes.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2014
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2014
CompletedFirst Submitted
Initial submission to the registry
February 5, 2016
CompletedFirst Posted
Study publicly available on registry
May 13, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2040
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 1, 2040
April 22, 2024
April 1, 2024
26.9 years
February 5, 2016
April 18, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (4)
Return to Performance- change in status
The Sports Surgery Clinic return to performance questionnaire asks whether the participant has returned to sport.
6,9,12 and 24 months post operatively
Injured operated knee- change in status
Participants are asked have they injured their operated knee.
6,9,12 and 24 months post operatively
Injured their contralateral knee- change in status
Participants are asked have they injured their operated knee.
6,9,12 and 24 months post operatively
Change in pain experienced
Participants will be asked to rate their pain on a numerical rating scale, 0-10.
6,9,12 and 24 months post operatively
Secondary Outcomes (2)
Change in Kinetic and kinematic composite score of the lower limb, pelvis and trunk
At 6 and 9 months post surgery
Change in International Knee Documentation Committee (IKDC)
3, 6, 9, 12 and 24 months post surgery
Study Arms (2)
Anterior Cruciate Ligament Reconstruction
Those who have undergone unilateral anterior cruciate ligament reconstructive surgery in the Sports Surgery Clinic.
Control
Healthy volunteers with no previous knee injury, no current lower limb injuries and take part in regular multidirectional team sports.
Interventions
Eligibility Criteria
Those who undergo anterior cruciate ligament reconstruction in the Sports Surgery Clinic, Dublin, and who meet the inclusion criteria, will be asked if they wish to participate in this study. Sports Surgery Clinic is a private hospital where over 750 ACL reconstructive surgeries take place each year. Many patients will travel from all over the country of Ireland to the clinic for the surgery, meaning there is a wide catchment area for participants.
You may qualify if:
- Active participants
- Anterior cruciate ligament reconstruction surgery in the Sports Surgery Clinic.
- Over the age of 13 years
You may not qualify if:
- Multiple orthopaedic injuries concurrently.
- Surgery outside of Sports Surgery Clinic.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Dr Neil Welch ASCClead
- Sports Surgery Clinic Research Foundationcollaborator
- Insight Centre for Data Analyticscollaborator
- Science Foundation Irelandcollaborator
- University of Roehamptoncollaborator
- University of Melbournecollaborator
- University College Corkcollaborator
- University of Leedscollaborator
- Children's Hospital Medical Center, Cincinnaticollaborator
Study Sites (1)
Sports Surgery Clinic
Dublin, Leinster, Ireland
Related Publications (12)
Boden BP, Griffin LY, Garrett WE Jr. Etiology and Prevention of Noncontact ACL Injury. Phys Sportsmed. 2000 Apr;28(4):53-60. doi: 10.3810/psm.2000.04.841.
PMID: 20086634BACKGROUNDKoga H, Nakamae A, Shima Y, Iwasa J, Myklebust G, Engebretsen L, Bahr R, Krosshaug T. Mechanisms for noncontact anterior cruciate ligament injuries: knee joint kinematics in 10 injury situations from female team handball and basketball. Am J Sports Med. 2010 Nov;38(11):2218-25. doi: 10.1177/0363546510373570. Epub 2010 Jul 1.
PMID: 20595545BACKGROUNDHiggins LD, Taylor MK, Park D, Ghodadra N, Marchant M, Pietrobon R, Cook C; International Knee Documentation Committee. Reliability and validity of the International Knee Documentation Committee (IKDC) Subjective Knee Form. Joint Bone Spine. 2007 Dec;74(6):594-9. doi: 10.1016/j.jbspin.2007.01.036. Epub 2007 Aug 6.
PMID: 17888709BACKGROUNDMarx RG, Stump TJ, Jones EC, Wickiewicz TL, Warren RF. Development and evaluation of an activity rating scale for disorders of the knee. Am J Sports Med. 2001 Mar-Apr;29(2):213-8. doi: 10.1177/03635465010290021601.
PMID: 11292048BACKGROUNDWebster KE, Feller JA, Lambros C. Development and preliminary validation of a scale to measure the psychological impact of returning to sport following anterior cruciate ligament reconstruction surgery. Phys Ther Sport. 2008 Feb;9(1):9-15. doi: 10.1016/j.ptsp.2007.09.003. Epub 2007 Nov 5.
PMID: 19083699BACKGROUNDBarber-Westin SD, Noyes FR, McCloskey JW. Rigorous statistical reliability, validity, and responsiveness testing of the Cincinnati knee rating system in 350 subjects with uninjured, injured, or anterior cruciate ligament-reconstructed knees. Am J Sports Med. 1999 Jul-Aug;27(4):402-16. doi: 10.1177/03635465990270040201.
PMID: 10424208BACKGROUNDPaterno MV, Schmitt LC, Ford KR, Rauh MJ, Myer GD, Huang B, Hewett TE. Biomechanical measures during landing and postural stability predict second anterior cruciate ligament injury after anterior cruciate ligament reconstruction and return to sport. Am J Sports Med. 2010 Oct;38(10):1968-78. doi: 10.1177/0363546510376053. Epub 2010 Aug 11.
PMID: 20702858BACKGROUNDMcAleese T, Welch N, King E, Roshan D, Keane N, Moran KA, Jackson M, Withers D, Moran R, Devitt BM. Primary Anterior Cruciate Ligament Reconstruction in Level 1 Athletes: Factors Associated With Return to Play, Reinjury, and Knee Function at 5 Years of Follow-up. Am J Sports Med. 2025 Mar;53(4):777-790. doi: 10.1177/03635465241313386. Epub 2025 Feb 7.
PMID: 39919304DERIVEDKing E, Richter C, Daniels KAJ, Franklyn-Miller A, Falvey E, Myer GD, Jackson M, Moran R, Strike S. Biomechanical but Not Strength or Performance Measures Differentiate Male Athletes Who Experience ACL Reinjury on Return to Level 1 Sports. Am J Sports Med. 2021 Mar;49(4):918-927. doi: 10.1177/0363546520988018. Epub 2021 Feb 22.
PMID: 33617291DERIVEDKing E, Richter C, Daniels KAJ, Franklyn-Miller A, Falvey E, Myer GD, Jackson M, Moran R, Strike S. Can Biomechanical Testing After Anterior Cruciate Ligament Reconstruction Identify Athletes at Risk for Subsequent ACL Injury to the Contralateral Uninjured Limb? Am J Sports Med. 2021 Mar;49(3):609-619. doi: 10.1177/0363546520985283. Epub 2021 Feb 9.
PMID: 33560866DERIVEDKing E, Richter C, Jackson M, Franklyn-Miller A, Falvey E, Myer GD, Strike S, Withers D, Moran R. Factors Influencing Return to Play and Second Anterior Cruciate Ligament Injury Rates in Level 1 Athletes After Primary Anterior Cruciate Ligament Reconstruction: 2-Year Follow-up on 1432 Reconstructions at a Single Center. Am J Sports Med. 2020 Mar;48(4):812-824. doi: 10.1177/0363546519900170. Epub 2020 Feb 7.
PMID: 32031870DERIVEDKing E, Richter C, Franklyn-Miller A, Wadey R, Moran R, Strike S. Back to Normal Symmetry? Biomechanical Variables Remain More Asymmetrical Than Normal During Jump and Change-of-Direction Testing 9 Months After Anterior Cruciate Ligament Reconstruction. Am J Sports Med. 2019 Apr;47(5):1175-1185. doi: 10.1177/0363546519830656.
PMID: 30943079DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Ray Moran, MCh (Orth) FRCSI FFSEM
Sports Surgery Clinic
- STUDY DIRECTOR
Mark Jackson, MBBS BSc FRCS
Sports Surgery Clinic
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 2 Years
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Head of lab services and research
Study Record Dates
First Submitted
February 5, 2016
First Posted
May 13, 2016
Study Start
January 1, 2014
Primary Completion (Estimated)
December 1, 2040
Study Completion (Estimated)
December 1, 2040
Last Updated
April 22, 2024
Record last verified: 2024-04