NCT02833454

Brief Summary

The purpose of the study is to study the effect of anatomical direct insertion ACL reconstruction compared with conventional anatomical ACL reconstruction.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
320

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jul 2016

Typical duration for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2016

Completed
10 days until next milestone

First Submitted

Initial submission to the registry

July 11, 2016

Completed
3 days until next milestone

First Posted

Study publicly available on registry

July 14, 2016

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2018

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2018

Completed
Last Updated

July 15, 2016

Status Verified

July 1, 2016

Enrollment Period

2 years

First QC Date

July 11, 2016

Last Update Submit

July 13, 2016

Conditions

Keywords

Anterior Cruciate Ligament ReconstructionDirect Insertion of Anterior Cruciate Ligament

Outcome Measures

Primary Outcomes (3)

  • Lysholm score of the knee

    Lysholm score of the knee was evaluated preoperatively and at 2 years post operation . Scale name:score

    two years

  • Tegner score of the knee

    Tegner score of the knee was evaluated preoperatively and at 2 years post operation . Scale name:score

    two years

  • IKDC score of the knee

    IKDC score of the knee was evaluated preoperatively and at 2 years post operation . Scale name:score

    two years

Secondary Outcomes (1)

  • KT-2000 of the knee

    two years

Study Arms (4)

direct insertion single bundle ACLR

ACTIVE COMPARATOR

Patients with ACL rupture undergo direct insertion anterior cruciate ligament reconstruction using single bundle technique.

Procedure: direct insertion anterior cruciate ligament reconstructionProcedure: single bundle anterior cruciate ligament reconstruction

anatomical double bundle ACLR

EXPERIMENTAL

Patients with ACL rupture undergo double bundle anterior cruciate ligament reconstruction.

Procedure: double bundle anterior cruciate ligament reconstruction

anatomical single bundle ACLR

EXPERIMENTAL

Patients with ACL rupture undergo single bundle anterior cruciate ligament reconstruction.

Procedure: single bundle anterior cruciate ligament reconstruction

direct insertion double bundle ACLR

ACTIVE COMPARATOR

Patients with ACL rupture undergo direct insertion anterior cruciate ligament reconstruction using double bundle technique.

Procedure: direct insertion anterior cruciate ligament reconstructionProcedure: double bundle anterior cruciate ligament reconstruction

Interventions

ACL reconstruction based on direct insertion of ACL.

direct insertion double bundle ACLRdirect insertion single bundle ACLR

anterior cruciate ligament reconstruction using single bundle technique

anatomical single bundle ACLRdirect insertion single bundle ACLR

anterior cruciate ligament reconstruction using double bundle technique

anatomical double bundle ACLRdirect insertion double bundle ACLR

Eligibility Criteria

Age16 Years - 40 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • ACL rupture patients aged between 16 to 40 years

You may not qualify if:

  • combined severe injuries to the operated knee (additional ligament rupture, major meniscus loss, patella instability, cartilage damage \>2°, pathologic leg axis deviation)
  • any injury or surgery to the contralateral knee
  • any infammatory or systemic disease, neuromuscular disease in the lower limbs, any recent knee infection

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Anterior Cruciate Ligament Injuries

Condition Hierarchy (Ancestors)

Knee InjuriesLeg InjuriesWounds and Injuries

Study Officials

  • Jia-Kuo Yu, MD

    Peking University Third Hospital

    STUDY CHAIR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

July 11, 2016

First Posted

July 14, 2016

Study Start

July 1, 2016

Primary Completion

July 1, 2018

Study Completion

August 1, 2018

Last Updated

July 15, 2016

Record last verified: 2016-07