An Interocular Comparative Study of Unilateral Cataract

NCT02765230 | Completed DMC

• 1 other identifier: CCPMOH2016-China-3
• Study Type: observational
• Target: 53
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this cross-sectional study is to compare bilateral anterior segment parameters, macular thickness, and BCVA at 3 months after uncomplicated unilateral pediatric cataract extraction with primary IOL implantation to explore any possible interocular differences and their possible relationships.

Conditions

Cataract

Outcome Measures

Primary Outcomes (2)

• Interocular anatomical parameters in pediatric unilateral cataract patients measured by pentacam

  The Parameters are measured by pentacam (Oculus Inc., Wetzlar, Germany), a rotating Scheimpflug camera.

  Baseline

• Visual function in pediatric unilateral cataract patients measured by Teller Acuity Cards

  The visual function is measured by Teller Acuity Cards (Stereo Optical Company, Inc., IL, USA).

  Baseline

Eligibility Criteria

• Age: Up to 10 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Probability Sample

Study Population

All of the registered children of CCPMOH were diagnosed by anterior segmental photography to confirm the morphology, location, and degree of cataract after pupil dilation. Fifty-three pediatric patients (53 cataract eyes and 53 contralateral normal eyes) with uncomplicated unilateral total cataract were selected 3 months after surgery from the CCPMOH.

You may qualify if:

• Children with uncomplicated surgeries
• Children who were younger than 10 years old
• Children with unilateral total cataract

You may not qualify if:

• Premature birth
• Microphthalmia
• Micro-or Megalocornea
• Keratoconus
• Glaucoma
• Traumatic or complicated cataracts
• Vitreous and retinal diseases
• Any previous surgeries

Sponsors & Collaborators

• Sun Yat-sen University: lead
• Ministry of Health, China: collaborator

Study Sites (1)

Zhongshan Ophthalmic Center, Sun Yat-sen University

Guangzhou, Guangdong, 510060, China

Location

Related Publications (3)

• Hutcheson KA. Application of new ophthalmic technology in the pediatric patient. Curr Opin Ophthalmol. 2007 Sep;18(5):384-91. doi: 10.1097/ICU.0b013e328244e07e.

  PMID: 17700231 BACKGROUND

• Lin H, Chen W, Luo L, Congdon N, Zhang X, Zhong X, Liu Z, Chen W, Wu C, Zheng D, Deng D, Ye S, Lin Z, Zou X, Liu Y. Effectiveness of a short message reminder in increasing compliance with pediatric cataract treatment: a randomized trial. Ophthalmology. 2012 Dec;119(12):2463-70. doi: 10.1016/j.ophtha.2012.06.046. Epub 2012 Aug 24.

  PMID: 22921386 BACKGROUND

• Long E, Chen J, Liu Z, Lin Z, Cao Q, Zhang X, Li X, Luo L, Lin H, Chen W, Liu Y. Interocular anatomical and visual functional differences in pediatric patients with unilateral cataracts. BMC Ophthalmol. 2016 Nov 3;16(1):192. doi: 10.1186/s12886-016-0371-5.

  PMID: 27809833 DERIVED

Related Links

• Description Home page of Zhongshan Ophthalmic Center

MeSH Terms

Conditions

Cataract

Condition Hierarchy (Ancestors)

Lens Diseases; Eye Diseases

Study Officials

• Haotian Lin, M.D., Ph.D

  Zhongshan Ophthalmic Center, Sun Yat-sen University

  PRINCIPAL INVESTIGATOR

• Yizhi Liu, M.D., Ph.D

  Zhongshan Ophthalmic Center, Sun Yat-sen University

  STUDY CHAIR

• Weirong Chen, M.D.

  Zhongshan Ophthalmic Center, Sun Yat-sen University

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator, Home for Cataract Children, Zhongshan Ophthalmic Center

Study Record Dates

• First Submitted: May 3, 2016
• First Posted: May 6, 2016
• Study Start: January 1, 2014
• Primary Completion: January 1, 2016
• Study Completion: January 1, 2016
• Last Updated: May 6, 2016

Record last verified: 2016-05

Locations

CN (1)