NCT02761928|Terminated
Study Stopped
Insufficient enrollment, lack of funding to continue
Investigation of Hypermobility, Biomarkers, and Pain Generators in Chronic Pain Patients
Hypermoble
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Sponsor study identifier
observational
31
1 country
1
Study Start
January 2016
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
August 1, 2017
Actual (reported)Study Completion
August 1, 2017
Actual (reported)Observational study of axial spine pain and hyperflexibility. Patients will receive physical exam maneuvers (traditional straight leg raise, FABER, facet loading as well as Beighton's hypermobility score) and blood / urine / saliva collection. They will also be separated into pain groups based on their response to injections. A correlation between exam findings and procedure group will be measured.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
August 1, 2017
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 2016
Date type not reportedThis date has not been verified as actual or estimated.
April 24, 2016
Actual (reported)May 4, 2016
Actual (reported)August 1, 2017
Actual (reported)August 1, 2017
Actual (reported)Beighton hypermobility score
9 point standardized scale
Prior to injection (2 weeks prior to injection for each patient)
Positive response (\>50% pain relief) to any epidural (e.g. interlaminar/paramedian, transforaminal, caudal)
Positive response (\>50% pain relief) to selective nerve root block
Positive response (\>50% pain relief) to intra-articular facet injection
Positive response (\>50% pain relief) to median branch nerve block
Positive response (\>50% pain relief) to median branch nerve radiofrequency ablation
The beighton score is a 9 point score of flexibility, used for patients with disorders of collagen.
Patients with low back pain who are determined to be candidates for a pain procedure
University of Texas Health Science Center at Houston
Houston, Texas, 77030, United States
Grahame R. Joint hypermobility syndrome pain. Curr Pain Headache Rep. 2009 Dec;13(6):427-33. doi: 10.1007/s11916-009-0070-5.
Blood, urine, saliva
Mark Burish, MD PhD
The University of Texas Health Science Center, Houston
31 participants (actual enrollment reported by the registry).
First Submitted
April 24, 2016
First Posted
May 4, 2016
Study Start
January 2016
Date type not reportedThis date has not been verified as actual or estimated.
Comparative Trial Via Tranforaminal Approach Versus Epidural Catheter Via Interlaminar Approach
Positive response (\>50% pain relief) to sacroiliac joint injection
Positive response (\>50% pain relief) to lateral branch nerve block for SIJ
Positive response (\>50% pain relief) to greater trochanteric bursa injection
Positive response (\>50% pain relief) to piriformis injection
Positive response (\>50% pain relief) to trigger point injection
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Contact the study team to confirm eligibility.
Primary Completion
August 1, 2017
Actual (reported)Study Completion
August 1, 2017
Actual (reported)Last Updated
November 12, 2020
Record last verified: 2020-11
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
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