NCT02761837

Brief Summary

The Breathe Well Study is a pragmatic, controlled trial to assess the effectiveness, cost-effectiveness, and implementation of the Breathe Well intervention, which combines evidence-based EHR and interactive behavior-change technologies (IBCT) and team-based care to improve asthma outcomes.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
14,978

participants targeted

Target at P75+ for not_applicable asthma

Timeline
Completed

Started Oct 2016

Longer than P75 for not_applicable asthma

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 28, 2016

Completed
6 days until next milestone

First Posted

Study publicly available on registry

May 4, 2016

Completed
5 months until next milestone

Study Start

First participant enrolled

October 1, 2016

Completed
6.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2023

Completed
Last Updated

November 9, 2023

Status Verified

November 1, 2023

Enrollment Period

6.7 years

First QC Date

April 28, 2016

Last Update Submit

November 7, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Asthma Exacerbations

    Defined as number of urgent care visits, hospitalizations, or prescriptions of an oral corticosteroid

    12 months

Secondary Outcomes (1)

  • Controller medication adherence

    12 months

Study Arms (2)

IVR call/text

ACTIVE COMPARATOR

Identify gaps in care and contact patients by IVR phone call or text

Behavioral: IVR call/text

Email

ACTIVE COMPARATOR

Identify gaps in care and contact patients by email

Behavioral: Email

Interventions

IVR call/textBEHAVIORAL

For patients under filling their inhaled corticosteroid or overusing B-agonist, the patient is contacted via IVR call or text

IVR call/text
EmailBEHAVIORAL

Patients under filling their inhaled corticosteroid or overusing B-agonist, the the patient is contacted via email

Email

Eligibility Criteria

Age19 Years - 99 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • B-agonist overfilling
  • inhaled corticosteroid (ICS) underfilling
  • current smoker
  • asthma exacerbation in the last year

You may not qualify if:

  • limited life expectancy
  • diagnosis of chronic obstructive pulmonary disease
  • lack of a pharmacy benefit because medication use cannot be captured.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kaiser Permanente of Colorado

Denver, Colorado, 80231, United States

Location

Related Publications (2)

  • Bender BG, Cvietusa PJ, Goodrich GK, King DK, Shoup JA. Adapting adaptive design methods to accelerate adoption of a digital asthma management intervention. Transl Behav Med. 2023 Apr 3;13(3):149-155. doi: 10.1093/tbm/ibac093.

  • Cvietusa PJ, Wagner NM, Shoup JA, Goodrich GK, Shetterly SM, King DK, Raebel MA, Riggs CS, Bender B. Digital Communication Technology: Does Offering a Choice of Modality Improve Medication Adherence and Outcomes in a Persistent Asthma Population? Perm J. 2020 Dec;25:1. doi: 10.7812/TPP/20.189.

MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Masking Details
This is a pragmatic controlled trial. Participants randomized to the intervention group will know when they receive the intervention, which will consist of an automated contact by IVR call/text, or email.
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Model Details: Participants were randomized to either 1) usual care or 2) Interactive Voice Response (IVR) or 3) email. Those in the groups 2 or 3 will receive the intervention only if they smoke, underuse controller medication, or overuse rescue medication.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 28, 2016

First Posted

May 4, 2016

Study Start

October 1, 2016

Primary Completion

June 1, 2023

Study Completion

June 1, 2023

Last Updated

November 9, 2023

Record last verified: 2023-11

Locations