Thrombolytic Care During Inter-hospital Transfer
Quality and Effectiveness of Thrombolytic Care During Inter-hospital Transfer ("Drip-Ship") With Air Ambulance Services
1 other identifier
observational
76
1 country
1
Brief Summary
Evaluation of ischemic stroke patients receiving tissue plasminogen activator (rtPA) during air ambulance transfer
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Oct 2015
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2015
CompletedFirst Submitted
Initial submission to the registry
April 18, 2016
CompletedFirst Posted
Study publicly available on registry
April 26, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2017
CompletedResults Posted
Study results publicly available
July 5, 2019
CompletedJuly 5, 2019
June 1, 2019
2 years
April 18, 2016
January 11, 2019
June 28, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Percentage of Participants With a rtPA Protocol Violation
Protocol violations can include any of the following recorded outcomes: inaccurate dosing or preparation at the outside hospital, uncontrolled blood pressure before and during the flight, unnecessary medication administration before and during the flight, intracranial bleeding, and angioedema
24 hours
Secondary Outcomes (1)
Average Time to rtPA
24 hours
Study Arms (2)
Intervention/Transfer
Patients who are transferred via air ambulance to a comprehensive stroke center
Control
Patients presenting directly to the comprehensive stroke center
Interventions
Eligibility Criteria
All acute ischemic stroke patients who receive rtPA and transferred to our institution via our air ambulance service or present directly to our ED
You may qualify if:
- Patients who received tissue plasminogen activator for acute ischemic stroke
- presented directly to comprehensive stroke center or were transferred by our air ambulance service
You may not qualify if:
- Transferred by another air ambulance service or ground ambulance
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Iowa Hospitals and Clinics
Iowa City, Iowa, 52242, United States
Related Publications (1)
Faine BA, Dayal S, Kumar R, Lentz SR, Leira EC. Helicopter "Drip and Ship" Flights Do Not Alter the Pharmacological Integrity of rtPA. J Stroke Cerebrovasc Dis. 2018 Oct;27(10):2720-2724. doi: 10.1016/j.jstrokecerebrovasdis.2018.05.049. Epub 2018 Jul 20.
PMID: 30037651DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Results Point of Contact
- Title
- Brett Faine
- Organization
- University of Iowa Hospitals and Clinics
Publication Agreements
- PI is Sponsor Employee
- No
- Restrictive Agreement
- No
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Clinical Pharmacy Specialist
Study Record Dates
First Submitted
April 18, 2016
First Posted
April 26, 2016
Study Start
October 1, 2015
Primary Completion
October 1, 2017
Study Completion
October 1, 2017
Last Updated
July 5, 2019
Results First Posted
July 5, 2019
Record last verified: 2019-06