NCT02745522

Brief Summary

The current study aimed to investigate whether oxytocin (OXT) had effect on placebo effect.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
224

participants targeted

Target at P75+ for phase_1

Timeline
Completed

Started Dec 2015

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2015

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

March 11, 2016

Completed
1 month until next milestone

First Posted

Study publicly available on registry

April 20, 2016

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2017

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2017

Completed
Last Updated

October 15, 2018

Status Verified

October 1, 2018

Enrollment Period

1.2 years

First QC Date

March 11, 2016

Last Update Submit

October 10, 2018

Conditions

Oxytocin Effect on Memory Performance During Phase 1Oxytocin Effect on Memory Performance During Phase 2Oxytocin Effect on Memory Performance During Phase 3Oxytocin Effect on Memory Performance During Phase 4

Keywords

Placebo effectWorking memory

Outcome Measures

Primary Outcomes (1)

  • Memory performance in different phases

    N-back memory performance (accuracy) was included into analysis.

    1 hour

Study Arms (2)

Oxytocin

EXPERIMENTAL

Oxytocin nasal spray

Drug: Oxytocin

Placebo

PLACEBO COMPARATOR

Placebo nasal spray

Drug: Placebo

Interventions

OxytocinDRUG
Oxytocin
PlaceboDRUG
Placebo

Eligibility Criteria

Age18 Years - 30 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy subjects without past or current psychiatric or neurological disorder

You may not qualify if:

  • history of head injury;
  • claustrophobia;
  • medical or psychiatric illness.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

School of Life Science and Technology, University of Electronic Science and Technology

Chengdu, Sichuan, 611731, China

Location

MeSH Terms

Interventions

Oxytocin

Intervention Hierarchy (Ancestors)

Pituitary Hormones, PosteriorPituitary HormonesPeptide HormonesHormonesHormones, Hormone Substitutes, and Hormone AntagonistsPeptidesAmino Acids, Peptides, and Proteins

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof.

Study Record Dates

First Submitted

March 11, 2016

First Posted

April 20, 2016

Study Start

December 1, 2015

Primary Completion

March 1, 2017

Study Completion

August 1, 2017

Last Updated

October 15, 2018

Record last verified: 2018-10

Locations

CN(1)