Assessing the Feasibility of Integrating Maternal Nutrition Interventions Into an Existing MNCH Platform in Bangladesh

NCT02745249 | Completed

• 1 other identifier: 2015-32-PHND-M
• Study Type: interventional
• Target: 3,500
• Locations: 1 country
• Sites: 1

Brief Summary

Inadequate maternal nutrition is likely to undermine the potential impact of infant and young child feeding (IYCF) improvements made in the Alive \& Thrive (A\&T) first phase because it is linked to poor fetal growth leading to small-for-gestational age and pre-term newborns. These babies do not respond to growth promoting feeding practices as well as normal newborns do. In Phase 2, Alive \& Thrive decided to focus on integrating a package of maternal nutrition interventions in a large-scale maternal, newborn and child health program (MNCH). This proposed evaluation aims to assess the feasibility of integrating maternal nutrition interventions into an existing MNCH platform in Bangladesh, using a cluster-randomized evaluation design.

Conditions

Poor Fetal Growth; Small-for-gestational Age; Premature Birth

Outcome Measures

Primary Outcomes (5)

• Use of iron-folic acid supplements

  Recall the total number of IFA tablets consumed throughout the last pregnancy

  IFA tablets used during 9 months of last pregnancy among recently delivered women with children <6 months of age by June 2016

• Use of calcium supplements

  Recall the total number of calcium tablets consumed throughout the last pregnancy

  Calcium tablets used during 9 months of last pregnancy among recently delivered women with children <6 months of age by June 2016

• Dietary diversity during pregnancy

  Number of food groups women consumed

  Pregnant women in second and third trimester of pregnancy (4-9 months) by June- August 2016

• Dietary micronutrient intakes

  Quantity of micronutrient intakes using 24-hour recall complemented by food weighing.

  Pregnant women in second and third trimester of pregnancy (4-9 months) by June- August 2016

• Coverage of maternal nutrition intervention

  The proportion of pregnant and recently delivery women expose to and use of MNCH platform during the last 1 year

  1 year

Secondary Outcomes (2)

• Early initiation of breastfeeding

  Infants up to 6 months in a cross-sectional endline survey scheduled for June- August 2016

• Exclusive breastfeeding

  Infants up to 6 months in a cross-sectional endline survey scheduled for June- August 2016

Study Arms (2)

A&T- intensive

EXPERIMENTAL

A\&T-intensive arm receive standard MNCH services and intensified maternal nutrition behavior change intervention which focus on improving dietary practices, specifically improved diversity of foods and energy intakes of pregnant women, and improved intake of calcium and iron/folic acid (IFA) supplements.

Behavioral: Maternal Nutrition Behavior change

A&T-non intensive

NO INTERVENTION

A\&T-non intensive aim only receive MNCH services

Interventions

Maternal Nutrition Behavior change BEHAVIORAL

A&T- intensive

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Recently delivered women with children \<6 months of age
• Pregnant women in second and third trimester and her husbands
• Frontline health workers in the areas

You may not qualify if:

• Age \<18
• Mental disorders that cannot understand and answer the questions

Sponsors & Collaborators

• International Food Policy Research Institute: lead

Study Sites (1)

International Food Policy Research Institute

Washington D.C., District of Columbia, 20006, United States

Location

Related Publications (4)

• Nguyen PH, Martin-Prevel Y, Moursi M, Tran LM, Menon P, Ruel MT, Arimond M. Assessing Dietary Diversity in Pregnant Women: Relative Validity of the List-Based and Open Recall Methods. Curr Dev Nutr. 2019 Nov 18;4(1):nzz134. doi: 10.1093/cdn/nzz134. eCollection 2020 Jan.

  PMID: 32258987 DERIVED

• Frongillo EA, Nguyen PH, Sanghvi T, Mahmud Z, Aktar B, Alayon S, Menon P. Nutrition Interventions Integrated into an Existing Maternal, Neonatal, and Child Health Program Reduce Food Insecurity Among Recently Delivered and Pregnant Women in Bangladesh. J Nutr. 2019 Jan 1;149(1):159-166. doi: 10.1093/jn/nxy249.

  PMID: 30649523 DERIVED

• Nguyen PH, Frongillo EA, Sanghvi T, Wable G, Mahmud Z, Tran LM, Aktar B, Afsana K, Alayon S, Ruel MT, Menon P. Engagement of Husbands in a Maternal Nutrition Program Substantially Contributed to Greater Intake of Micronutrient Supplements and Dietary Diversity during Pregnancy: Results of a Cluster-Randomized Program Evaluation in Bangladesh. J Nutr. 2018 Aug 1;148(8):1352-1363. doi: 10.1093/jn/nxy090.

  PMID: 29931108 DERIVED

• Nguyen PH, Kim SS, Sanghvi T, Mahmud Z, Tran LM, Shabnam S, Aktar B, Haque R, Afsana K, Frongillo EA, Ruel MT, Menon P. Integrating Nutrition Interventions into an Existing Maternal, Neonatal, and Child Health Program Increased Maternal Dietary Diversity, Micronutrient Intake, and Exclusive Breastfeeding Practices in Bangladesh: Results of a Cluster-Randomized Program Evaluation. J Nutr. 2017 Dec;147(12):2326-2337. doi: 10.3945/jn.117.257303. Epub 2017 Oct 11.

  PMID: 29021370 DERIVED

MeSH Terms

Conditions

Fetal Growth Retardation; Premature Birth

Condition Hierarchy (Ancestors)

Fetal Diseases; Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Growth Disorders; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Obstetric Labor, Premature; Obstetric Labor Complications

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 1, 2016
• First Posted: April 20, 2016
• Study Start: July 1, 2015
• Primary Completion: October 1, 2016
• Study Completion: October 1, 2016
• Last Updated: September 27, 2017

Record last verified: 2017-09

Locations

US (1)