NCT02740101

Brief Summary

To examine potential differential effects of receiving various social feedback on achieving personal goals,and whether oxytocin would modulate these effects.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
62

participants targeted

Target at P75+ for early_phase_1 healthy

Timeline
Completed

Started Nov 2014

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2014

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2015

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2015

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

March 21, 2016

Completed
25 days until next milestone

First Posted

Study publicly available on registry

April 15, 2016

Completed
Last Updated

March 6, 2017

Status Verified

March 1, 2017

Enrollment Period

9 months

First QC Date

March 21, 2016

Last Update Submit

March 2, 2017

Conditions

Healthy

Keywords

oxytocinsocial rewardsocial punishment

Outcome Measures

Primary Outcomes (1)

  • Rating of Encouragement after receiving specific social feedback

    There're 96 different social feedback totally for four goals which were divided into four runs consisting of 24 different feedback separately for each goal video.Therefore,subjects were instructed to complete the encouragement rating after receiving each specific feedback. To measure the rating,the investigators used the 9-point likert scale in which one refers to the minimum encouragement while nine refers to maximum encouragement.

    one hour

Secondary Outcomes (1)

  • Rating of Likeability after receiving specific social feedback

    one hour

Other Outcomes (1)

  • Rating of Confidence after receiving a series of social feedback

    one hour

Study Arms (2)

oxytocin nasal spray

EXPERIMENTAL

subjects administrating oxytocin were divided into experimental group

Drug: oxytocin treatment

placebo nasal spray

PLACEBO COMPARATOR

subjects administrating placebo were divided into controlled group

Drug: placebo treatment

Interventions

oxytocin treatmentDRUG

intranasal administration of oxytocin (40 IU)

oxytocin nasal spray
placebo treatmentDRUG

intranasal administration of placebo (40 IU)

placebo nasal spray

Eligibility Criteria

Age18 Years - 30 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy subjects without past or current psychiatric or neurological disorders.

You may not qualify if:

  • Taking oral contraceptives;
  • No history of head injury and medical or psychiatric illness.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

school of life science and technology, University of Electronic Science and Technology of China

Chengdu, Sichuan, 610054, China

Location

Study Officials

  • Keith Kendrick, Dr.

    University of Electronic Science and Technology of China

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
early phase 1
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

March 21, 2016

First Posted

April 15, 2016

Study Start

November 1, 2014

Primary Completion

August 1, 2015

Study Completion

October 1, 2015

Last Updated

March 6, 2017

Record last verified: 2017-03

Locations

CN(1)