Short-and Long-term Effects of a Home-based Rehabilitation Program in Patients With Bronchiectasis

NCT02731482 | Completed

• 1 other identifier: Bronchiectasis Rehabilitation
• Study Type: interventional
• Target: 66
• Locations: 1 country
• Sites: 1

Brief Summary

This study will investigate the short-and long-term effects of the home-based pulmonary rehabilitation on peripheral muscle strength, functional capacity and quality of life in patients with bronchiectasis. The participants will be randomized into two groups: control group (usual care and recommendations for practice exercise) and training group, that will perform aerobic (stepping training) and resistance training (lower and upper limbs) for eight weeks, three times a week. At baseline, immediately after finishing and after six months the patients will undergo assessments.

Conditions

Bronchiectasis

Keywords

Bronchiectasis; Rehabilitation; Quality of Life; Physiotherapy Specialty

Outcome Measures

Primary Outcomes (1)

• Distance, in meters, performed in the Incremental Shuttle Walk Test

  Measurement of functional capacity and exercise tolerance

  up to 9 months

Secondary Outcomes (5)

• Time, in seconds, performed in the Endurance Shuttle Walk Test

  up to 9 monthsst

• Number of steps performed in the Incremental Step Test

  up to 9 months

• Physical functioning domain scale in the Quality of Life Questionnaire-Bronchiectasis (QoL-B)

  up to 9 months

• Kilogram-force (kgf) of quadriceps femoris

  up to 9 months

• Number of steps per day, measured by a pedometer

  up to 9 months

Study Arms (2)

Training Group

EXPERIMENTAL

Patients with bronchiectasis in home-based pulmonary rehabilitation

Other: Training Group

Control Group

ACTIVE COMPARATOR

Patients with bronchiectasis in usual care and recommendations for performing exercises

Other: Control Group

Interventions

Training Group OTHER

Three sessions per week, each lasting 50 minutes, during eight weeks. * Aerobic training in stepping training. * Resistance training: Three sets of eight repetitions each, in both simultaneous members, using an elastic band. The trained muscles are quadriceps, hamstrings, deltoid and biceps. * Once a week, patients will receive a phone call and every two weeks, patients will get a visit of the researcher at his home.

Also known as: Physical training intervention

Training Group

Control Group OTHER

* The participants will receive verbal and written information about the importance of physical activity and walk in moderate intensity, at least, three times a week for 30 minutes. * Participants will not receive any supervised physical training. * Once a week, patients will receive a phone call to provide support and general advice.

Also known as: Physical activity intervention

Control Group

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Clinical diagnosis and/or tomographic bronchiectasis Clinically stable (no change in symptoms of dyspnea, in the amount and color of the secretion) Have completed the outpatient pulmonary rehabilitation for more than a year Not engaged in a regular physical activity.

You may not qualify if:

• Smokers With other lung related diseases (asthma, COPD and cystic fibrosis) Severe cardiovascular diseases Musculoskeletal limitation Unable to perform the tests and the training protocol due desaturation (pulse oxygen saturation ≤ 80%) over the recommended exercise intensity.

Sponsors & Collaborators

• University of Nove de Julho: lead
• University of Sao Paulo: collaborator

Study Sites (1)

Universidade Nove de Julho

São Paulo, 01504-001, Brazil

Location

Related Publications (1)

• Jose A, Holland AE, Oliveira CS, Selman JPR, Castro RAS, Athanazio RA, Rached SZ, Cukier A, Stelmach R, Corso SD. Does home-based pulmonary rehabilitation improve functional capacity, peripheral muscle strength and quality of life in patients with bronchiectasis compared to standard care? Braz J Phys Ther. 2017 Nov-Dec;21(6):473-480. doi: 10.1016/j.bjpt.2017.06.021. Epub 2017 Aug 19.

  PMID: 28869119 DERIVED

MeSH Terms

Conditions

Bronchiectasis

Interventions

Sensitivity Training Groups; Control Groups

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Psychotherapy, Group; Socioenvironmental Therapy; Psychotherapy; Behavioral Disciplines and Activities; Epidemiologic Research Design; Epidemiologic Methods; Investigative Techniques; Research Design; Methods

Study Officials

• Simone Dal Corso, PT, PhD

  University of Nove de Julho

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PT, PhD

Study Record Dates

• First Submitted: March 30, 2016
• First Posted: April 7, 2016
• Study Start: June 1, 2016
• Primary Completion: August 1, 2019
• Study Completion: August 1, 2019
• Last Updated: August 16, 2019

Record last verified: 2019-08

Data Sharing

• IPD Sharing: Will not share

Locations

BR (1)