NCT02729337

Brief Summary

The investigators propose to develop a comprehensive, text messaging-based HIV prevention program for Ugandan adolescents 18-22 years of age.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
203

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Dec 2017

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 15, 2016

Completed
22 days until next milestone

First Posted

Study publicly available on registry

April 6, 2016

Completed
1.7 years until next milestone

Study Start

First participant enrolled

December 6, 2017

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 18, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 18, 2019

Completed
Last Updated

February 18, 2020

Status Verified

February 1, 2020

Enrollment Period

1.1 years

First QC Date

March 15, 2016

Last Update Submit

February 14, 2020

Conditions

Keywords

technologyadolescentdeveloping countryhiv preventionmHealth

Outcome Measures

Primary Outcomes (3)

  • Program feasibility: Recruitment

    The number of participants recruited for the RCT (n=200)

    24 weeks

  • Program feasibility: Retention

    The number of participants that will remain in the study at program end (80%)

    Through study completion, an average of 6 weeks

  • Program acceptability as assessed by a scale created for the RCT

    Participant ratings of program features (e.g., Text Buddy) at intervention end

    At intervention end, 6-weeks post baseline

Secondary Outcomes (3)

  • Percent of participants reporting condom use during sex as assessed by self-report

    At intervention end, 6-weeks post baseline

  • Percent of participants reporting abstinence as assessed by self-report

    At intervention end, 6-weeks post baseline

  • Percent of participants who have gotten an HIV test as assessed by self-report

    At intervention end, 6-weeks post baseline

Study Arms (2)

ITG (In This Together)

EXPERIMENTAL

This will be a multi-week behavioral intervention delivered daily via text messaging. Content will be based upon the IMB model of HIV preventive behavior and informed by our formative work.

Behavioral: ITG (In This Together)

Control Group

NO INTERVENTION

Given the preliminary nature of the intervention development, the control group will be inactive but blinded. They will receive two messages per week encouraging them to make healthy sexual decisions to reduce their HIV risk. Messages will be didactic and not driven by the IMB model.

Interventions

Comprehensive, mHealth-based HIV prevention program for Ugandan adolescents 18-22 years of age.

ITG (In This Together)

Eligibility Criteria

Age18 Years - 22 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • living in Uganda
  • aged 18-22 years
  • able to read English
  • exclusive owner of a cell phone
  • using text messaging for at least 6 months
  • intended to have the same phone number or the next six months
  • able to access the Internet (to complete online surveys)
  • able to provide informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Internet Solutions for Kids Uganda

Mbarara, Uganda

Location

Related Publications (1)

  • Ybarra ML, Agaba E, Nyemara N. A Pilot RCT Evaluating InThistoGether, an mHealth HIV Prevention Program for Ugandan Youth. AIDS Behav. 2021 Oct;25(10):3437-3448. doi: 10.1007/s10461-021-03237-5. Epub 2021 May 7.

MeSH Terms

Conditions

Sexual AbstinenceContraception Behavior

Condition Hierarchy (Ancestors)

Sexual BehaviorBehaviorReproductive Behavior

Study Officials

  • Michele Ybarra, MPH PHD

    Center for Innovative Public Health Research

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 15, 2016

First Posted

April 6, 2016

Study Start

December 6, 2017

Primary Completion

January 18, 2019

Study Completion

January 18, 2019

Last Updated

February 18, 2020

Record last verified: 2020-02

Locations