Comparative Study of Two Embryo Culture Systems
INCUBATE
1 other identifier
observational
388
1 country
1
Brief Summary
The centre for Medically-Assisted Procreation (MAP) of Dijon CHU has two high-technology embryo culture systems, with incubation characteristics that are potentially superior to those provided by classical culture systems. Indeed, these two systems, available in only two MAP centres in France, make it possible to maintain a stable temperature and gaseous environment during the in-vitro development of the embryos. It is necessary to observe the development of the embryos to determine which embryos have the highest implantation potential. These observations are done from time to time by microscope for one system and continuously using an incorporated video camera for the other (cinematographic study). The MAP centre in Dijon wishes to compare the interest of these two systems.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Aug 2014
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 27, 2014
CompletedFirst Submitted
Initial submission to the registry
March 18, 2016
CompletedFirst Posted
Study publicly available on registry
March 29, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 29, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
March 29, 2017
CompletedFebruary 6, 2026
February 1, 2026
2.6 years
March 18, 2016
February 4, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Implantation rate
The implantation rate is defined as the number of embryos implanted (gestational sacs seen on the US scan) compared to the total number of embryos transferred.
16 weeks after transfer
Secondary Outcomes (1)
Rate of miscarriages
16 weeks after transfer
Study Arms (2)
Embryoscope group
Embryo culture without incorporated camera group
Interventions
Eligibility Criteria
Couples who attempt In Vitro Fertilization with ICSI (IntraCytoplasmic Sperm Injection)
You may qualify if:
- Persons who have provided oral consent
- Attempt at In Vitro Fertilization with ICSI (IntraCytoplasmic Sperm Injection)
- At least 6 mature ovocytes to microinject
You may not qualify if:
- Persons not covered by national health insurance
- Attempt at In Vitro Fertilization (IVF)
- Fewer than 6 mature ovocytes
- Decision to transfer at the zygote stage during the multidisciplinary meeting
- Attempts made in a context of viral risk (both systems are in a virus risk-free zone)
- Attempts with surgically-harvested spermatozoa
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
CHU de DIJON
Dijon, 21079, France
Related Publications (1)
Barberet J, Chammas J, Bruno C, Valot E, Vuillemin C, Jonval L, Choux C, Sagot P, Soudry A, Fauque P. Randomized controlled trial comparing embryo culture in two incubator systems: G185 K-System versus EmbryoScope. Fertil Steril. 2018 Feb;109(2):302-309.e1. doi: 10.1016/j.fertnstert.2017.10.008. Epub 2017 Nov 23.
PMID: 29175066RESULT
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 18, 2016
First Posted
March 29, 2016
Study Start
August 27, 2014
Primary Completion
March 29, 2017
Study Completion
March 29, 2017
Last Updated
February 6, 2026
Record last verified: 2026-02