NCT03522350

Brief Summary

The purpose of the study is to compare the current EmbryoScope Time-Lapse System being used in IVF which has become standard of care to the new model EmbryoScope to demonstrate that the EmbryoScope+ is as safe and reliable as the EmbryoScope.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
18

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Sep 2017

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 6, 2017

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

February 20, 2018

Completed
3 months until next milestone

First Posted

Study publicly available on registry

May 11, 2018

Completed
24 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 4, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 4, 2018

Completed
12 months until next milestone

Results Posted

Study results publicly available

May 31, 2019

Completed
Last Updated

May 31, 2019

Status Verified

May 1, 2019

Enrollment Period

9 months

First QC Date

February 20, 2018

Results QC Date

May 6, 2019

Last Update Submit

May 6, 2019

Conditions

Keywords

InfertilityEmbryo develpomentIVFICSIEmbryoScope

Outcome Measures

Primary Outcomes (2)

  • Number of Day 3 Embryos

    Comparing number of embryos that fertilized normally and had development at Day 3 based on embryo grade between oocytes assigned to Standard EmbryoScope versus oocytes assigned to EmbryoScope+

    Day 3 post retrieval

  • Number of Day 5 Embryos

    Comparing the number pf embryos that developed at Day 5 based on embryo grade between oocytes assigned to Standard EmbryoScope versus oocytes assigned to EmbryoScope+

    Day 5 post retrieval

Secondary Outcomes (2)

  • Implantation Rate

    5-6 weeks post retrieval

  • Pregnancy Rate

    2 weeks post retrieval

Study Arms (2)

EmbryoScope

ACTIVE COMPARATOR

Standard of care embryo incubator.

Device: EmbryoScope

EmbryoScope+

EXPERIMENTAL

New experimental embryo incubator.

Device: EmbryoScope+

Interventions

Experimental arm

EmbryoScope+

Eligibility Criteria

Age18 Years - 65 Years
Sexall(Gender-based eligibility)
Gender Eligibility DetailsMaternal age- 40 years of age or younger Paternal age- 65 years of age or younger
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years of age or younger (maternal)
  • years of age or younger (paternal)
  • Fresh or frozen (including donor) sperm can be used
  • Fresh oocytes only (including donor)
  • Frozen embryos from this study can be included in the outcome portion of this study.
  • Single or double Blastocyst transfer only

You may not qualify if:

  • or more previous failed cycles
  • Sperm obtained by testicular biopsy
  • Co-culture patients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Center for Reproductive Medicine

New York, New York, 10065, United States

Location

MeSH Terms

Conditions

Infertility

Interventions

Fetoscopes

Condition Hierarchy (Ancestors)

Genital DiseasesUrogenital Diseases

Intervention Hierarchy (Ancestors)

EndoscopesDiagnostic EquipmentEquipment and SuppliesSurgical Equipment

Results Point of Contact

Title
Nikica Zaninovic, PhD
Organization
Weill Cornell Medical College

Study Officials

  • Nikica Zaninovic, PhD

    Center for Reproductive Medicine

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 20, 2018

First Posted

May 11, 2018

Study Start

September 6, 2017

Primary Completion

June 4, 2018

Study Completion

June 4, 2018

Last Updated

May 31, 2019

Results First Posted

May 31, 2019

Record last verified: 2019-05

Data Sharing

IPD Sharing
Will not share

Locations